Validating PD Cognitive Profiles. Substudy: White Matter Connectivity and PD Cognitive Phenotypes


The purpose of this research study is to investigate 1) brain and blood markers of memory and thinking difficulties in Parkinson’s disease, and 2) how these markers can predict different memory and thinking difficulties over a period of two years. Individuals diagnosed with Parkinson’s disease are being compared to individuals who do not have Parkinson’s disease.


  • Screening to determine eligibility includes gathering demographic information and cognitive testing 
  • If you meet study criteria, then you will be formally enrolled in the study. Being in the study requires three visits over a two-year period.
  • If you wish to continue your participation, we ask that you come in for annual follow-up visits at three and four-year time points here at UF&Shands.
  • Each visit will involve cognitive and memory testing and a fasting blood draw.
  • This can be completed over a one or two day visit for each time point, depending on your preference.
  • A brain MRI will only be conducted during your first visit.
  • If you are from out of town, we will provide you and a spouse/companion with a no-cost 1-2 night stay within a local hotel in order to alleviate travel demands and make the process more convenient for you.
  • During the visit, we will reimburse you for mileage to and from UF&Shands.


You may qualify for this study if you:

  • Have symptoms of Parkinson's disease
  • OR you may qualify to be in a non-Parkinson’s comparison group
  • The research procedures are the same for both groups 

For additional study information such as details about procedures and eligibility criteria, please reach out to the Catherine Price: 


65 and over



Monetary compensation


Can be done from home



Parkinson disease, Parkinson's disease, Parkinson’s disease - resources, Neurology, healthy volunteers

Principal Investigator

Catherine Price, PhD, ABPP

Contact Information

(352) 273-5929

Be an Informed Participant

Before deciding to participate in a research study, take time to learn about clinical research, how it's conducted and your rights as a research participant. Following are some helpful resources from independent sources. Always remember that a clinical research study is research, not treatment.

Know Who to Contact

  • Eligibility: For questions about a specific study and who is eligible to participate, call or email the contact person listed for that study.
  • Your Rights: For questions about your rights as a research participant, contact the UF Institutional Review Boards at 352-273-9600.
  • Feedback: For general questions or feedback about study listings, email the UF Clinical and Translational Science Institute at

Other Resources

  • HealthStreet: Health-focused services, classes and events, and opportunities to participate in research.
  • Join a national registry of volunteers willing to be contacted about research studies.

For Research Teams