Carol Mathews, M.D. - Research & Publications

Publications

Concordance of genetic variation that increases risk for Tourette syndrome and that influences its underlying neurocircuitry
Translational Psychiatry
2019

Challenges and lessons learned from clinical pharmacogenetic implementation of multiple gene-drug pairs across ambulatory care settings
Genetics in Medicine
2019

Relationship between symptom severity, psychiatric comorbidity, social/occupational impairment, and suicidality in hoarding disorder
Journal of Obsessive-Compulsive and Related Disorders
2018

Randomised clinical trial of community-based peer-led and psychologist-led group treatment for hoarding disorder.
BJPsych open
2018

Prevalence and Predictors of Hair Pulling Disorder and Excoriation Disorder in Tourette Syndrome
European Child & Adolescent Psychiatry
2018

Polygenic Risk Scores Derived From a Tourette Syndrome Genome-wide Association Study Predict Presence of Tics in the Avon Longitudinal Study of Parents and Children Cohort
Biological Psychiatry
2018

Genetic and Phenotypic Overlap of Specific Obsessive-Compulsive and Attention-Deficit/Hyperactive Subtypes With Tourette Syndrome
Psychological Medicine
2018

Examination of the shared genetic basis of anorexia nervosa and obsessive-compulsive disorder.
Molecular Psychiatry
2018

Error-processing and inhibitory control in obsessive-compulsive disorder: a meta-analysis using statistical parametric maps
Biological Psychiatry
2018

Detail-oriented visual processing style: Its role in the relationships between early life adversity and hoarding-related dysfunctions.
Psychiatry Research
2018

Deficits in Physiological and Self-Conscious Emotional Response to Errors in Hoarding Disorder
Psychiatry Research
2018

De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis.
Cell Reports
2018

Contributions of Self-Criticism and Shame to Hoarding
Psychiatry Research
2018

Analysis of Shared Heritability in Common Disorders of the Brain
Science (New York, N.Y.)
2018

The Role of Regional Conferences in Research Resident Career Development: The California Psychiatry Research Resident Retreat
Academic Psychiatry
2017

Revealing the complex genetic architecture of obsessive-compulsive disorder using meta-analysis
Molecular Psychiatry
2017

Rare Synaptogenesis-Impairing Mutations in SLITRK5 Are Associated with Obsessive Compulsive Disorder
PLoS One (Journal)
2017

Rare Copy Number Variants in Nrxn1 and Cntn6 Increase Risk for Tourette Syndrome
Neuron
2017

Parental psychopathology and Tourette Syndrome/chronic tic disorder in offspring: a nationwide case-control study
Journal of the American Academy of Child and Adolescent Psychiatry
2017

Integrating Evolutionary and Regulatory Information With Multispecies Approach Implicates Genes and Pathways in Obsessive-Compulsive Disorder
Nature Communications
2017

Institutional Profile: University of Florida Health Personalized Medicine Program
Pharmacogenomics
2017

Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome
American Journal of Psychiatry
2017

Heritability of Tic Disorders: a Twin-Family Study
Psychological Medicine
2017

Gilles De La Tourette Syndrome
Nature Reviews Disease Primers
2017

De Novo Coding Variants Are Strongly Associated With Tourette Disorder
Neuron
2017

Autism Spectrum Symptoms in a Tourette's Disorder Sample
Journal of the American Academy of Child and Adolescent Psychiatry
2017

Age-specific prevalence of hoarding and obsessive compulsive disorder: a population-based study
The American Journal Of Geriatric Psychiatry : Official Journal Of The American Association For Geriatric Psychiatry
2017

A Model-Based Analysis of Decision Making Under Risk in Obsessive-Compulsive and Hoarding Disorders
Journal of Psychiatric Research
2017

Treating Hoarding Disorder in a real world setting: Results from the Mental Health Association of San Francisco
Psychiatry Research
2016

The relationship between tics, OC, ADHD, and autism symptoms: A cross-disorder symptom analysis in Gilles de la Tourette syndrome patients and family-members
Psychiatry Research
2016

The Genetic Etiology of Tourette Syndrome: Large-Scale Collaborative Efforts on the Precipice of Discovery

2016

The First World Congress on Tourette Syndrome and Tic Disorders: Controversies and Hot Topics in Etiology and Treatment

2016

The Association Between Psychiatric Disorders and Telomere Length: a Meta-Analysis Involving 14, 827 Persons
Psychosomatic Medicine
2016

Social disinhibition is a heritable subphenotype of tics in Tourette syndrome
Neurology
2016

Patterns of clinically significant cognitive impairment in hoarding disorder
Depression and Anxiety
2016

Hazardous Drinking Among Young Adults Seeking Outpatient Mental Health Services
Addiction Science & Clinical Practice
2016

Error-Related Brain Activity Dissociates Hoarding Disorder From Obsessive-Compulsive Disorder
Psychological Medicine
2016

Comparison of a Peer Facilitated Support Group to Cognitive Behavior Therapy: Study Protocol for a Randomized Controlled Trial for Hoarding Disorder
Contemporary Clinical Trials
2016

Comparison of Brain Activation Patterns During Executive Function Tasks in Hoarding Disorder and Non-Hoarding Ocd
Psychiatry Research-Neuroimaging
2016

Clinical Correlates of Hoarding With and Without Comorbid Obsessive-Compulsive Symptoms in a Community Pediatric Sample
Journal of the American Academy of Child and Adolescent Psychiatry
2016

Analysis of protein-coding genetic variation in 60,706 humans
Nature
2016

Web-Based Phenotyping for Tourette Syndrome: Reliability of Common Co-Morbid Diagnoses
Psychiatry Research
2015

Tourette Syndrome: Complementary Insights from Measures of Cognitive Control, Eyeblink Rate, and Pupil Diameter
Front Psychiatry
2015

Tic symptom dimensions and their heritabilities in Tourette's syndrome
Psychiatric Genetics
2015

Population prevalence of Tourette syndrome: A systematic review and meta-analysis
Movement Disorders
2015

Parental mood during pregnancy and post-natally is associated with offspring risk of Tourette syndrome or chronic tics: prospective data from the Avon Longitudinal Study of Parents and Children
European Child & Adolescent Psychiatry
2015

Neuropsychological and dimensional behavioral trait profiles in Costa Rican ADHD sib pairs: Potential intermediate phenotypes for genetic studies
American Journal of Medical Genetics
2015

Lifetime prevalence, age of risk, and genetic relationships of comorbid psychiatric disorders in Tourette syndrome
JAMA psychiatry
2015

Involvement of astrocyte metabolic coupling in Tourette syndrome pathogenesis
European Journal of Human Genetics
2015

Cross-Disorder Genome-Wide Analyses Suggest a Complex Genetic Relationship Between Tourette's Syndrome and OCD
American Journal of Psychiatry
2015

COMT and MAO-A polymorphisms and obsessive-compulsive disorder: a family-based association study
Plos One
2015

Tourette syndrome and chronic tic disorder are associated with lower socio-economic status: findings from the Avon Longitudinal Study of Parents and Children cohort
Developmental Medicine and Child Neurology
2014

Partitioning the etiology of hoarding and obsessive-compulsive symptoms
Psychological Medicine
2014

Identification of the hikikomori syndrome of social withdrawal: Psychosocial features and treatment preferences in four countries
The International journal of social psychiatry
2014

Genetic association signal near NTN4 in Tourette syndrome
Annals of Neurology
2014

Copy number variation in obsessive-compulsive disorder and tourette syndrome: a cross-disorder study
Journal of the American Academy of Child and Adolescent Psychiatry
2014

Association between pre- and perinatal exposures and Tourette syndrome or chronic tic disorder in the ALSPAC cohort.
British Journal of Psychiatry
2014

Prevalence and clinical correlates of explosive outbursts in Tourette syndrome
Psychiatry Research
2013

Partitioning the heritability of tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture
Plos Genetics
2013

Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1
American Journal of Medical Genetics
2013

Genome-wide association study of obsessive-compulsive disorder
Molecular Psychiatry
2013

Genome-wide association study of Tourette's syndrome
Molecular Psychiatry
2013

Eleven-year outcomes from an integrated residency program to train research psychiatrists
Academic Emergency Medicine
2013

CNV Analysis in Tourette Syndrome Implicates Large Genomic Rearrangements in COL8A1 and NRXN1
Plos One
2013

Prevalence of tourette syndrome and chronic tics in the population-based Avon longitudinal study of parents and children cohort
Journal of the American Academy of Child and Adolescent Psychiatry
2012

Genome-wide linkage analysis of obsessive-compulsive disorder implicates chromosome 1p36
Biological Psychiatry
2012

Error-related negativity in individuals with obsessive-compulsive symptoms: Toward an understanding of hoarding behaviors
Biological Psychiatry
2012

Effectiveness of a Web-Based Protocol for the Screening and Phenotyping of Individuals with Tourette Syndrome for Genetic Studies
American Journal of Medical Genetics
2012

Characteristics and co-morbidity of ADHD sib pairs in the Central Valley of Costa Rica
Comprehensive Psychiatry
2012

Prevalence of and screening for ADHD in Costa Rica
Vertex
2011

Latent class analysis of YBOCS symptoms in Obsessive Compulsive Disorder
Comprehensive Psychiatry
2011

Genomewide Linkage Analysis in Costa Rican Families Implicates Chromosome 15q14 as a Candidate Region for OCD
Human Genetics
2011

Family-based genetic association study of DLGAP3 in Tourette Syndrome
American Journal of Medical Genetics
2011

Familiality of Tourette Syndrome, Obsessive-Compulsive Disorder, and Attention Deficit Hyperactivity Disorder: Heritability Analyses in a Large Affected-Sib Pair Sample
Journal of the American Academy of Child and Adolescent Psychiatry
2011

Cognitive functioning in individuals with severe compulsive hoarding behaviors and late life depression
International Journal of Geriatric Psychiatry
2011

Brain-derived neurotrophic factor (BDNF) plasma levels in drug-naïve OCD patients are lower than those in healthy people, but are not lower than those in drug-treated OCD patients
Journal of Affective Disorders
2011

Symptom dimensions in OCD: Item-level factor analysis and heritability estimates
Behavior Genetics
2010

ADHD prevalence and association with hoarding behaviors in childhood-onset OCD
Depression and Anxiety
2010

Linkage analysis of Tourette syndrome in a large Utah pedigree
American Journal of Medical Genetics
2010

Clinical phenomenology and phenotype variability in Tourette syndrome
Journal of Psychosomatic Research
2009

A narrow and highly significant linkage signal for severe bipolar disorder in the chromosome 5q33 region in Latin American pedigrees
American Journal of Medical Genetics
2009

Latent Class Analysis of Gilles de la Tourette Syndrome Using Comorbidities: Clinical and Genetic Implications
Biological Psychiatry
2008

Lack of association between SLITRK1var321 and Tourette syndrome in a large family-based sample
Neurology
2008

Evidence for a heritable unidimensional symptom factor underlying obsessionality
American Journal of Medical Genetics
2008

Childhood trauma and obsessive-compulsive symptoms
Depression and Anxiety
2008

A comparative study of obsessive-compulsive disorder in Costa Rica and the US
Depression and Anxiety
2008

Tic symptom profiles in subjects with Tourette Syndrome from two genetically isolated populations
Biological Psychiatry
2007

Heritability and clinical features of multigenerational families with obsessive-compulsive disorder and hoarding
American Journal of Medical Genetics
2007

Anxiety symptoms and perceived performance in medical students
Depression and Anxiety
2007

Results of a SNP genome screen in a large Costa Rican pedigree segregating for severe bipolar disorder
American Journal of Medical Genetics
2006

Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses
Human Molecular Genetics
2006

Genome Scan for Tourette's Disorder in Affected Sib-Pair and Multigenerational Families
American Journal of Human Genetics
2006

Convergent linkage evidence from two Latin-American population isolates supports the presence of a susceptibility locus for bipolar disorder in 5q31-34
Human Molecular Genetics
2006

Association between maternal smoking and increased symptom severity in Tourette Syndrome
American Journal of Psychiatry
2006

Sequence Variants in SLITRK1 Are Associated with Tourette's Syndrome
Science
2005

The structure of obsessionality in young adults
Depression and Anxiety
2004

Self-injurious behaviour in Tourette syndrome: correlates with impulsivity and impulse control
Journal of Neurology Neurosurgery and Psychiatry
2004

Genetic Studies of Neuropsychiatric Disorders in Central America. Psychiatric Genetics
Psychiatric Genetics
2004

Meta-analysis of the association between the catecholamine-O-methyl-transferase gene and obsessive-compulsive disorder
American Journal of Medical Genetics
2003

CNTNAP2 is disrupted in a family with Gilles de la Tourette syndrome and obsessive compulsive disorder
Current Genomics
2003

The Effect on Treatment Outcomes of Assigning Patients to Ethnically Focused Inpatient Psychiatric Units
Psychiatric Services
2002

The Effect on Diagnostic Rates of Assigning Patients to Ethnically Focused Inpatient Psychiatric Units
Psychiatric Services
2002

Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolate
American Journal of Human Genetics
2002

Genome Wide Scan of Hoarding in Sibling Pairs Both Diagnosed with Gilles de la Tourette Syndrome
American Journal of Human Genetics
2002

Comorbidity of bipolar disorder and substance abuse in a Latin American population: Pedigree and population based studies
Journal of Affective Disorders
2002

Genome screening for linkage disequilibrium in a Costa Rican sample of patients with bipolar-I disorder: a follow-up study on chromosome 18
American Journal of Medical Genetics
2001

Fine scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population
Proceedings of the National Academy of Sciences of the United States of America
2001

Cultural effects on diagnosis and perception of Tourette Syndrome in Costa Rica
Journal of the American Academy of Child and Adolescent Psychiatry
2001

Assortative mating in bipolar disorder: A systematic review and meta-analysis
Comprehensive Psychiatry
2001

Cardiofaciocutaneous syndrome
Jama Dermatology
1993