UF Health MedMatters

UF Researchers Investigating Alzheimer’s From Multiple Directions

Stefan ProkopInvestigators at the University of Florida are searching for keys to understanding Alzheimer’s disease. Stefan Prokop, MD, is among the dozens of researchers at UF trying to determine the cause of Alzheimer’s by examining a protein called beta-amyloid that clumps into plaques between neurons and a protein called tau that abnormally accumulates inside neurons to form tangled threads known as neurofibrillary tangles.

Prokop, who leads the neuropathology core of the 1Florida Alzheimer’s Disease Research Center, a UF-led consortium of top research institutions commonly referred to as the 1Florida ADRC, is also working to examine brains from diverse racial backgrounds. One focus that distinguishes the 1Florida ADRC from 32 other such Alzheimer’s Disease Research Centers around the country is that over 60% of participants are Hispanic.

Other researchers at the University of Florida, including Dr. Malú Gámez Tansey, are looking at Alzheimer’s from a different perspective. Her research focuses on the roles of inflammation and the immune system in the development and progression of neurodegenerative diseases.

Read more about how researchers across the University of Florida are working to understand Alzheimer’s disease. You can also listen to the article here.

About UF Health Shands Hospital

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University of Florida Health Shands Hospital has been recognized among the nation’s best hospitals in seven adult medical specialties. Overall, UF Health Shands Hospital was recognized as one of the best hospitals in Florida. In addition to being ranked among the nation’s top 50 hospitals in seven specialties, UF Health Shands Hospital also was listed as “high performing” in seven specialties, including abdominal aortic aneurysm repair, colon cancer surgery, COPD, heart failure, lung cancer surgery, neurology & neurosurgery and orthopaedics.