Shawn Larson, MD

Shawn D Larson, MD, FACS

(352) 265-8800

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Publications

T-Cell Activation and LPS: A Dangerous Duo for Organ Dysfunction.
Journal of leukocyte biology
2022

Social determinants of health in pediatric scald burns: Is food access an issue?
Surgery
2022

Monocyte anisocytosis increases during multisystem inflammatory syndrome in children with cardiovascular complications.
BMC infectious diseases
2022

Medical Student Career Choice: Who Is the Influencer?
The Journal of surgical research
2022

Heterogeneity in the evaluation of suspected MIS-C: a cross-sectional vignette-based survey.
BMC pediatrics
2022

Enterobius vermicularis-associated appendicitis: A 22-year case series and comprehensive review of the literature.
Journal of pediatric surgery
2022

Correction to: Monocyte anisocytosis increases during multisystem inflammatory syndrome in children with cardiovascular complications.
BMC infectious diseases
2022

Prehospital personnel discretion pediatric trauma team activations: Too much of a good thing?
Journal of pediatric surgery
2021

Chronic “sepsis brain” and regulatory T cells – A promising therapeutic target
Brain, Behavior, and Immunity
2021

Cecal Slurry Injection in Neonatal and Adult Mice.
Methods in molecular biology (Clifton, N.J.)
2021

Analysis of Outcomes in Adolescents and Young Adults With Pilonidal Disease.
Frontiers in surgery
2021

Aluminum Adjuvant Improves Survival Via NLRP3 Inflammasome and Myeloid Non-Granulocytic Cells in a Murine Model of Neonatal Sepsis.
Shock (Augusta, Ga.)
2021

The Clinical Presentation and Immunology of Viral Pneumonia and Implications for Management of Coronavirus Disease 2019.
Critical care explorations
2020

Pediatric earlobe keloids: Outcomes and patterns of recurrence.
Journal of pediatric surgery
2020

Outcomes After Prehospital Endotracheal Intubation in Suburban/Rural Pediatric Trauma.
The Journal of surgical research
2020

Immunological Endotyping of Chronic Critical Illness After Severe Sepsis.
Frontiers in medicine
2020

Commentary: Letter to the Editor "Austere Environments Consortium for Enhanced Sepsis Outcomes (ACESO)".
Shock (Augusta, Ga.)
2020

What's New in Shock, December 2019?
Shock (Augusta, Ga.)
2019

Long-term outcomes of antegrade continence enema in children with chronic encopresis and incontinence: what is the optimal flush to use?
Pediatric surgery international
2019

Sepsis is associated with reduced spontaneous neutrophil migration velocity in human adults.
PloS one
2018

Review: The Perioperative Use of Thromboelastography for Liver Transplant Patients.
Transplantation proceedings
2018

Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy.
Frontiers in immunology
2018

Initial primary spontaneous pneumothorax in children and adolescents: Operate or wait?
Journal of pediatric surgery
2018

Inguinal hernias in premature neonates: exploring optimal timing for repair.
Pediatric surgery international
2018

Impact of toll-like receptor 4 stimulation on human neonatal neutrophil spontaneous migration, transcriptomics, and cytokine production
Journal of Molecular Medicine
2018

Duodenal web presenting outside the neonatal period concurrently with malrotation and mid-gut volvulus
Journal of Pediatric Surgery Case Reports
2018

Delayed Healing Associated with Silver Sulfadiazine Use for Partial Thickness Scald Burns in Children.
The American surgeon
2018

Adjuvant pretreatment with alum protects neonatal mice in sepsis through myeloid cell activation
Clinical and Experimental Immunology
2018

Unique transcriptomic response to sepsis is observed among patients of different age groups.
PloS one
2017

Severe Neonatal Purpura Fulminans Caused By Staphylococcus Aureus
Clinical Pediatrics
2017

Neutrophil chemotaxis and transcriptomics in term and preterm neonates
Translational Research
2017

Microbial recognition and danger signals in sepsis and trauma.
Biochimica et biophysica acta. Molecular basis of disease
2017

LPS Stimulation of Cord Blood Reveals a Newborn-Specific Neutrophil Transcriptomic Response and Cytokine Production.
Shock (Augusta, Ga.)
2017

Impact of Early-Life Exposures to Infections, Antibiotics, and Vaccines on Perinatal and Long-term Health and Disease.
Frontiers in immunology
2017

Immunological Defects in Neonatal Sepsis and Potential Therapeutic Approaches.
Frontiers in pediatrics
2017

Pediatric sepsis.
Current opinion in pediatrics
2016

Patterns of gene expression among murine models of hemorrhagic shock/trauma and sepsis.
Physiological genomics
2016

Improved Survival in Left Liver-Up Congenital Diaphragmatic Hernia by Early Repair Before Extracorporeal Membrane Oxygenation: Optimization of Patient Selection by Multivariate Risk Modeling.
Journal of the American College of Surgeons
2016

Outcomes in the physiologically most severe congenital diaphragmatic hernia (CDH) patients: Whom should we treat?
Journal of pediatric surgery
2015

Improved emergency myelopoiesis and survival in neonatal sepsis by caspase-1/11 ablation.
Immunology
2015

Delayed emergency myelopoiesis following polymicrobial sepsis in neonates.
Innate immunity
2015

Alum as a Preventative Therapy Abolishes Mortality in Murine Neonatal Sepsis By Improving Effector Cell Function and Bacterial Clearance
Shock
2015

Protective immunity and defects in the neonatal and elderly immune response to sepsis.
Journal of immunology (Baltimore, Md. : 1950)
2014

Ogilvie's syndrome after pediatric spinal deformity surgery: successful treatment with neostigmine.
Journal of neurosurgery. Pediatrics
2014

Feasibility of Laparoscopic Pyloromyotomy Under Spinal Anesthesia
Journal of Pediatric Surgery
2014

Extracorporeal life support in patients with congenital diaphragmatic hernia: how long should we treat?
Journal of the American College of Surgeons
2014

Enhanced Protective Immunity and Extramedullary Myelopoiesis in Neonatal Sepsis By Ablation of Caspase-1 Signaling
Shock
2014

Appendiceal carcinoids in children--management and outcomes.
The Journal of surgical research
2014

Long-term maturation of congenital diaphragmatic hernia treatment results: toward development of a severity-specific treatment algorithm.
Annals of surgery
2013

Development and characterization of a novel in vivo model of carcinoid syndrome.
Clinical cancer research : an official journal of the American Association for Cancer Research
2009

PI3K/Akt activation is critical for early hepatic regeneration after partial hepatectomy.
American journal of physiology. Gastrointestinal and liver physiology
2008

Meconium pseudocyst in a newborn.
Journal of the American College of Surgeons
2006

Research Interests

Dr. Larson is a Fellow of the American College of Surgeons (FACS) and the American Academy of Pediatrics (FAAP). Additionally, he is a member of the following organizations: American Pediatric Surgical Association (APSA), Society of University Surgeons (SUS; elected), Association for Academic Surgery (AAS), Pediatric Trauma Society (PTS), The Shock Society, and the Florida Chapters of the American College of Surgeons & American Academy of Pediatrics