A Study of Vericiguat in Participants With Heart Failure With Reduced Ejection Fraction (VICTORIA)


The purpose of this research study is to determine the safety and effectiveness of an experimental study drug (MK-1242) for the treatment of heart failure.


  • Visit with your doctor about 12 times throughout the study (1.5 - 3.5 years)
  • Take study medication as directed
  • Visits may include: blood samples, a physical exam, and optional heart imaging procedures


  • Heart failure
For additional eligibility criteria please contact the study team.


18 and under
18 to 65



Monetary compensation


Can be done from home



Heart failure - overview, Coronary heart disease, Cardiomyopathy

Principal Investigator

Juan Vilaro, MD


Division of Cardiology

Contact Information


(352) 273-8933

Be an Informed Participant

Before deciding to participate in a research study, take time to learn about clinical research, how it's conducted and your rights as a research participant. Following are some helpful resources from independent sources. Always remember that a clinical research study is research, not treatment.

Know Who to Contact

  • Eligibility: For questions about a specific study and who is eligible to participate, call or email the contact person listed for that study.
  • Your Rights: For questions about your rights as a research participant, contact the UF Institutional Review Boards at 352-273-9600.
  • Feedback: For general questions or feedback about study listings, email the UF Clinical and Translational Science Institute at UFStudies@health.ufl.edu.

Other Resources

  • HealthStreet: Health-focused services, classes and events, and opportunities to participate in research.
  • ResearchMatch.org: Join a national registry of volunteers willing to be contacted about research studies.

For Research Teams