A Study to Assess the Effects of a Medication in Patients with Angina


The purpose of this study is to evaluate the effects (possible risks and the effectiveness) of the investigational drug (drug that is not approved by the United States Food and Drug Administration (FDA)) SAR407899. This study will look at SAR407899 within the dose range between 2.5mg and 10mg, by mouth, twice daily compared to placebo (substance that contains no active medication).


  • Complete tests including a physical exam, blood sample, PET scan and ECG
  • Take study medication  
  • 6 visits over a 36 day period


  • Persistent stable chest pain
Please contact study team for additional eligibility criteria.


18 to 65
65 and over



Monetary compensation


Can be done from home



Angina, Chest pain, Stable angina

Principal Investigator

Carl Pepine, MD


Division of Cardiology

Contact Information


(352) 273-8933

Be an Informed Participant

Before deciding to participate in a research study, take time to learn about clinical research, how it's conducted and your rights as a research participant. Following are some helpful resources from independent sources. Always remember that a clinical research study is research, not treatment.

Know Who to Contact

  • Eligibility: For questions about a specific study and who is eligible to participate, call or email the contact person listed for that study.
  • Your Rights: For questions about your rights as a research participant, contact the UF Institutional Review Boards at 352-273-9600.
  • Feedback: For general questions or feedback about study listings, email the UF Clinical and Translational Science Institute at UFStudies@health.ufl.edu.

Other Resources

  • HealthStreet: Health-focused services, classes and events, and opportunities to participate in research.
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For Research Teams