NRG-BN001: Randomized Phase II Trial of Hypofractionated Dose-Escalated Photon IMRT or Proton Beam Therapy versus Conventional Photon Irradiation with Concomitant and adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma.
The purpose of the study is to determine if dose-escalated and -intensified photon IMRT or Proton beam therapy (using a dose-per-fraction escalation with simultaneous integrated boost) with concomitant and adjuvant temozolomide improves overall survival, as compared to standard-dose photon irradiation with concomitant and adjuvant temozolomide.
KeywordsBrain Tumors, Glioblastoma multiforme, Metastatic brain tumor, Glioma, tumor
Principal InvestigatorRonny Rotondo
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