R. David Anderson, MD

R. David D Anderson, MD, MS, FACC, FSCAI

(352) 265-0820

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Publications

The use of fascia iliaca block with minimal conscious sedation in transcatheter aortic valve replacement: Advances in TAVR anesthesia
Cardiovascular revascularization medicine : including molecular interventions
2020

Resting coronary velocity and myocardial performance in women with impaired coronary flow reserve: Results from the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD) study
International Journal of Cardiology
2020

Percutaneous inferior vena cava valve implantation may improve tricuspid valve regurgitation and cardiac output: Lessons learned
Innovations (Philadelphia, Pa. Online)
2020

Myocardial infarction and persistent angina with no obstructive coronary artery disease

2020

Incidence, Clinical Presentation, and Causes of 30-Day Readmission Following Hospitalization With Spontaneous Coronary Artery Dissection.
JACC. Cardiovascular interventions
2020

Does ischemia also change as we age?
Jacc-Cardiovascular Interventions
2020

Design, methodology and baseline characteristics of the Women’s Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD)
American heart journal (Online)
2020

Cardiovascular considerations for the internist and hospitalist in the COVID-19 era
The American journal of medicine
2020

Angina hospitalization rates in women with signs and symptoms of ischemia but no obstructive coronary artery disease: A report from the WISE (Women’s Ischemia Syndrome Evaluation) Study
Journal of the American Heart Association
2020

The functional assessment of patients with non-obstructive coronary artery disease: Expert review from an international microcirculation working group
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
2019

Prevalence of coronary endothelial and microvascular dysfunction in women with symptoms of ischemia and no obstructive coronary artery disease is confirmed by a new cohort: the NHLBI-sponsored Women’s Ischemia Syndrome Evaluation – Coronary Vascular Dysfunction (WISE-CVD)
Journal of Interventional Cardiology
2019

Outcomes of direct transcatheter aortic valve replacement without balloon aortic valvuloplasty using a new generation valve
Cardiovascular revascularization medicine : including molecular interventions
2019

Left ventricular concentric remodeling and functional impairment in women with ischemia with no obstructive coronary artery disease and intermediate coronary flow reserve: A report from the WISE-CVD Study
European heart journal. Cardiovascular imaging (Online)
2019

Is it time to eliminate balloon valvuloplasty before transcatheter aortic valve replacement?
International Journal of Cardiology
2019

Drug-Eluting Balloons Versus Everolimus-Eluting Stents for In-Stent Restenosis: A Meta-Analysis of Randomized Trials
Cardiovascular revascularization medicine : including molecular interventions
2019

Trends of Incidence, Clinical Presentation, and In-Hospital Mortality Among Women With Acute Myocardial Infarction With or Without Spontaneous Coronary Artery Dissection a Population-Based Analysis
Jacc-Cardiovascular Interventions
2018

Transcatheter Aortic Valve Replacement Efficiency and Safety Improvements With Progressive Experience and Improved Technology

2018

Temporal trends of inpatient use of intravascular imaging among patients undergoing percutaneous coronary intervention in the United States
Jacc-Cardiovascular Interventions
2018

Statin use in men and new onset of erectile dysfunction: A systematic review and meta-analysis
The American journal of medicine
2018

Safety and efficacy of second-generation drug-eluting stents compared with bare-metal stents: An updated meta-analysis and regression of 9 randomized clinical trials
Clinical Cardiology
2018

Prevalence, causes, and predictors of 30-day readmissions following hospitalization with acute myocardial infarction complicated by cardiogenic shock: Findings from the 2013-2014 National Readmissions Database
Journal of the American Heart Association
2018

Multisite Investigation of Outcomes With Implementation of Cyp2C19 Genotype-Guided Antiplatelet Therapy After Percutaneous Coronary Intervention
Jacc-Cardiovascular Interventions
2018

Meta-Analysis of Aspirin Versus Dual Antiplatelet Therapy Following Coronary Artery Bypass Grafting
American Journal of Cardiology
2018

Maladaptive Left Ventricular Remodeling in Women: An Analysis From the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Study
International Journal of Cardiology
2018

Intracoronary bolus injection versus intravenous infusion of adenosine for assessment of coronary flow velocity reserve in women with signs and symptoms of myocardial ischemia and no obstructive coronary artery disease
Jacc-Cardiovascular Interventions
2018

Efficiency improvements in the catheterization laboratory: It’s all about the team
Jacc-Cardiovascular Interventions
2018

Early and midterm outcomes of transcatheter aortic valve replacement in patients with bicuspid aortic valves.
Journal of Cardiac Surgery
2018

Current status of coronary atherectomy
Cardiovascular Innovations and Applications
2018

When ablation is not the answer: Acute left main thrombosis causing incessant ventricular tachycardia following left ventricular assist device implant
Cureus
2017

The Athena Trials: Autologous Adipose-Derived Regenerative Cells for Refractory Chronic Myocardial Ischemia With Left Ventricular Dysfunction
Catheterization and cardiovascular interventions.
2017

Staged Versus Index Procedure Complete Revascularization in St-Elevation Myocardial Infarction: a Meta-Analysis
Journal of Interventional Cardiology
2017

Safety and Efficacy of Dual Versus Triple Antithrombotic Therapy in Patients Undergoing Percutaneous Coronary Intervention
The American journal of medicine
2017

Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Disease: a Meta-Analysis and Regression of Randomized Trials
Catheterization and cardiovascular interventions.
2017

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: the Cctrn Pace Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells)
Circulation
2017

Early invasive strategy and in-hospital survival among diabetics with non-ST-elevation acute coronary syndromes: A contemporary national insight
Journal of the American Heart Association
2017

Daily Activity Measured With Wearable Technology As a Novel Measurement of Treatment Effect in Patients With Coronary Microvascular Dysfunction: Substudy of a Randomized Controlled Crossover Trial
JMIR research protocols
2017

Comparison of Periprocedural and Mid-Term Stroke Rates and Outcomes Between Surgical Aortic Valve Replacement and Transcatheter Aortic Valve Replacement Patients
Journal of Cardiovascular Surgery
2017

Cold Pressor Stress Cardiac Magnetic Resonance Myocardial Flow Reserve Is Not Useful for Detection of Coronary Endothelial Dysfunction in Women With Signs and Symptoms of Ischemia and No Obstructive Cad
PLoS One
2017

Cardiac pneumonia: Acute mitral regurgitation causing lobar infiltrate
The American journal of medicine
2017

Acetylcholine Versus Cold Pressor Testing for Evaluation of Coronary Endothelial Function
PLoS One
2017

Renal denervation: Past, present, and future
Cardiovascular Innovations and Applications
2016

Ranolazine in patients with incomplete revascularisation after percutaneous coronary intervention (RIVER-PCI): A multicentre, randomised, double-blind, placebo-controlled trial
Lancet
2016

Ixmyelocel-T for Patients With Ischaemic Heart Failure: a Prospective Randomised Double-Blind Trial
Lancet
2016

Does RIDDLE-NSTEMI provide an answer to the timing of ACS therapy?
Jacc-Cardiovascular Interventions
2016

Coronary artery chronic total occlusion
Cardiovascular Innovations and Applications
2016

Circulating Progenitor Cells and Coronary Microvascular Dysfunction: Results From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction Study (Wise-Cvd)
Atherosclerosis
2016

Association Between High Endocardial Unipolar Voltage and Improved Left Ventricular Function in Patients With Ischemic Cardiomyopathy
Texas Heart Institute journal
2016

Acute Kidney Injury After Transcatheter Aortic Valve Replacement
Journal of Cardiac Surgery
2016

A Randomized, Placebo-Controlled Trial of Late Na Current Inhibition (Ranolazine) in Coronary Microvascular Dysfunction (Cmd): Impact on Angina and Myocardial Perfusion Reserve
European heart journal
2016

The Coronary Microcirculation in STEMI: The Next Frontier?
European heart journal
2015

Relationships between components of metabolic syndrome and coronary intravascular ultrasound atherosclerosis measures in women without obstructive coronary artery disease: The NHLBI-sponsored Women’s Ischemia Syndrome Evaluation study
Cardiovascular endocrinology
2015

Long-term use of ticagrelor in patients with prior myocardial infarction
New England Journal of Medicine
2015

Cognitive-Motivational Influences On Health Behavior Change in Chronic Pain
Journal of Pain
2015

Changes in Ventricular Remodelling and Clinical Status During the Year Following a Single Administration of Stromal Cell-Derived Factor-1 Non-Viral Gene Therapy in Chronic Ischaemic Heart Failure Patients: the Stop-Hf Randomized Phase II Trial
European heart journal
2015

Are we there yet? Should all comatose cardiac arrest survivors go to the cath lab?
Jacc-Cardiovascular Interventions
2015

Acute kidney injury after transcatheter aortic valve replacement
American Journal of Nephrology
2015

Timi Frame Count and Adverse Events in Women With No Obstructive Coronary Disease: a Pilot Study From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
PLoS One
2014

Sdf-1 Plasmid Attenuates Adverse Remodeling in Ischemic Heart Failure Patients in a Randomized Phase II Trial

2014

Drug-Eluting Stents May Not Reduce Target Lesion Revascularization in Cardiac Allograft Vasculopathy
Journal of Interventional Cardiology
2014

Comparison of Low and High Dose Intracoronary Adenosine and Acetylcholine in Women Undergoing Coronary Reactivity Testing: Results From the Nhlbi-Sponsoredwomen's Ischemia Syndrome Evaluation (Wise)
International Journal of Cardiology
2014

Clinical Pharmacogenetics Implementation: Approaches, Successes, and Challenges
American Journal of Medical Genetics. Part C: Seminars in Medical Genetics
2014

Cardiovascular Cell Therapy Research Network. Rationale and design for PACE: Patients with intermittent claudication injected with ALDH bright cells
American heart journal (Online)
2014

Bone Marrow Mononuclear Cell Therapy for Acute Myocardial Infarction a Perspective From the Cardiovascular Cell Therapy Research Network
Circulation research
2014

Multimodality Direct Coronary Imaging With Combined Near-Infrared Spectroscopy and Intravascular Ultrasound: Initial Us Experience
Catheterization and cardiovascular interventions.
2013

Increased Circulating Progenitor Cells in Women With Microvascular Coronary Dysfunction: Results From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction Study (Wise-Cvd)
Circulation
2013

Electromechanical Assessment of Myocardial Function Is Associated With Improvement in Ejection Fraction in Patients Treated With Autologous Stem Cell Therapy for Ischemic Cardiomyopathy
Circulation
2013

Electromechanical Assessment of Myocardial Function (Noga) Is Associated With Exercise Improvement in Patients Treated With Autologous Stem Cell Therapy for Refractory Angina
Journal of the American College of Cardiology
2013

Coronary Angiography Is It Time To Reassess?
Circulation
2013

Adverse Outcomes Among Women Presenting With Signs and Symptoms of Ischemia and No Obstructive Coronary Artery Disease: Findings From the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (Wise) Angiographic Core Laboratory
American heart journal
2013

Strategies for multivessel revascularization in patients with diabetes
New England Journal of Medicine
2012

Simple Main Branch Only Stenting Is Preferable To Complex Bifurcation Intervention Regardless of the Side Branch Strategy: a Meta-Analysis of Randomized Clinical Trials
Journal of the American College of Cardiology
2012

Safety of Coronary Reactivity Testing in Women With No Obstructive Coronary Artery Disease
Jacc-Cardiovascular Interventions
2012

Relationships Between Components of Metabolic Syndrome and Coronary Intravascular Ultrasound (Ivus) Atherosclerosis Measures in Women Without Obstructive Coronary Artery Disease: the Nhlbi-Sponsored Women'S Ischemia Syndrome Evaluation (Wise) Study
Journal of the American College of Cardiology
2012

Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery On Left Ventricular Function After Acute Myocardial Infarction the Time Randomized Trial
Jama-Journal of the American Medical Association
2012

Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells On Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure the Focus-Cctrn Trial
Jama-Journal of the American Medical Association
2012

Differential Effects of Cold Pressor and Acetylcholine During Endothelial Function Assessment in Women With No Obstructive Coronary Artery Disease: the Nhlbi-Sponsored Women'S Ischemia Syndrome Evaluation (Wise) Study
Journal of the American College of Cardiology
2012

Relationship Between Coronary Micro- and Macrovascular Measures in Women With Chest Pain Without Significant Coronary Artery Disease: An Ancillary Substudy From the Nhbli-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Journal of the American College of Cardiology
2011

In Women With Symptoms of Cardiac Ischemia, Nonobstructive Coronary Arteries, and Microvascular Dysfunction, Angiotensin-Converting Enzyme Inhibition Is Associated With Improved Microvascular Function: a Double-Blind Randomized Study From the National Heart, Lung and Blood Institute Women'S Ischemia Syndrome Evaluation (Wise)
American heart journal
2011

Efficacy and Safety of Glycoprotein Iib/Iiia Inhibitors During Elective Coronary Revascularization a Meta-Analysis of Randomized Trials Performed in the Era of Stents and Thienopyridines
Journal of the American College of Cardiology
2011

Does Angiotensin Plus Aldosterone Inhibition Improve Coronary Endothelial Function? An Ancillary Study From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Journal of the American College of Cardiology
2011

Could Retinal Imaging Provide a Simple, Inexpensive, Noninvasive Index for Coronary Microvascular Function in Women With Chest Pain and Nonobstructive Coronary Artery Disease? An Ancillary Pilot Study From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise-Aric)
Journal of the American College of Cardiology
2011

A randomized two-by-two comparison of high-dose bolus tirofiban versus abciximab and unfractionated heparin versus bivalirudin during percutaneous coronary revascularization and stent placement: The tirofiban evaluation of novel dosing versus abciximab with clopidogrel and inhibition of thrombin (TENACITY) study trial
Catheterization and cardiovascular interventions.
2011

Outcomes Among Hypertensive Patients With Concomitant Peripheral and Coronary Artery Disease Findings From the International Verapamil-Sr/Trandolapril Study
Hypertension
2010

Left Internal Mammary Artery Graft Decompression By Covered Stent Treatment of An Adjacent Saphenous Vein Graft Pseudoaneurysm
Jacc-Cardiovascular Interventions
2010

Coronary Microvascular Reactivity To Adenosine Predicts Adverse Outcome in Women Evaluated for Suspected Ischemia Results From the National Heart, Lung and Blood Institute Wise (Women's Ischemia Syndrome Evaluation) Study
Journal of the American College of Cardiology
2010

An Intravascular Ultrasound Analysis in Women Experiencing Chest Pain in the Absence of Obstructive Coronary Artery Disease: a Substudy From the National Heart, Lung and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Journal of Interventional Cardiology
2010

Acute Evaluation of the Mynx (Tm) Vascular Closure Device During Arterial Re-Puncture in An Ovine Model
Journal of Invasive Cardiology
2009

Treatment of a Ruptured Saphenous Vein Graft Pseudoaneurysm Using a Vascular Plug
Catheterization and cardiovascular interventions.
2008

The Optimal Treatment of Carotid Atherosclerosis: a 2008 Update and Literature Review
Postgraduate Medicine
2008

Response To the J-Point Revisited
Hypertension
2008

Pulse Pressure and Adverse Outcomes in Women: a Report From the Women'S Ischemia Syndrome Evaluation (Wise)
American Journal of Hypertension
2008

Blood Pressure Targets After High-Risk Myocardial Infarction - Is It Time To Update the Guidelines?
Hypertension
2008

Results from a phase II multicenter, double-blind placebo-controlled study of Del-1 (VLTS-589) for intermittent claudication in subjects with peripheral arterial disease
American heart journal (Online)
2007

Gender differences in the treatment for acute myocardial infarction: Bias or biology?
Circulation
2007

Therapeutic angiogenesis with recombinant fibroblast growth factor-2 for intermittent claudication (the TRAFFIC study): A randomized trial
Lancet
2002

Predicting outcome after thrombolysis in acute myocardial infarction according to ST-segment resolution at 90 minutes: A substudy of the GUSTO-III trial. Global Use of Strategies To Open occluded coronary arteries
American heart journal (Online)
2002

Does the presence of thrombus seen on a coronary angiogram affect the outcome after percutaneous coronary angioplasty? An Angiographic Trials Pool data experience
Journal of the American College of Cardiology
2001

Design of the Therapeutic Angiogenesis with Recombinant Fibroblast Growth Factor-2 for Intermittent Claudication (TRAFFIC) trial
American Journal of Cardiology
2001

Lack of progress in cardiogrenic shock: Lessons from the GUSTO trials
European heart journal
2000

Prognostic value of congestive heart failure history in patients undergoing percutaneous coronary interventions
Journal of the American College of Cardiology
1998

Use of intraaortic balloon counterpulsation in patients presenting with cardiogenic shock: observations from the GUSTO-I Study. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries
Journal of the American College of Cardiology
1997

Relationship between diabetes mellitus and long-term survival after coronary bypass and angioplasty
Circulation
1997

New concept in coronary angioplasty: Dilatation with a helical balloon that allows simultaneous autoperfusion
Catheterization And Cardiovascular Diagnosis
1997

Coronary artery angioplasty with a helical autoperfusion balloon catheter
Catheterization And Cardiovascular Diagnosis
1997

A comparison of reteplase with alteplase for acute myocardial infarction
New England Journal of Medicine
1997

The effect of intra-aortic balloon counterpulsation on coronary blood flow velocity distal to coronary artery stenoses
Cardiology
1996

Successful identification and management of high-risk patients with acute myocardial infarction
Journal of thrombosis and thrombolysis (Dordrecht. Online)
1996

Arterial diastolic pressure augmentation by intra-aortic balloon counterpulsation enhances the onset of coronary artery reperfusion by thrombolytic therapy
Circulation
1994

Accelerated intravenous dosing of recombinant tissue-type plasminogen activator causes rapid but unstable reperfusion in a canine model of acute myocardial infarction
Coronary Artery Disease
1994

A canine model of acute coronary artery thrombosis for the evaluation of reperfusion strategies
Cardiology
1994

Research Interests

Dr. Anderson has continued interest and participation in clinical trials of device and drug development for both stable coronary artery disease and acute coronary syndromes. His interests also include the application of advanced interventional techniques including rotational and orbital atherectomy, embolic protection, and thrombectomy in the treatment of both coronary artery and peripheral arterial disease. Dr. Anderson is involved in clinical trials of novel and interventional-based treatments for resistant hypertension. He has established a multi-disciplinary clinic for the evaluation and treatment of aortic valve disease to include percutaneous valve therapy. Dr. Anderson has participated in the design and execution of multiple clinical trials involving the use of angiogenesis growth factors in the treatment of peripheral arterial disease and is actively involved in ongoing clinical trials of cardiac regeneration therapy using stem cells. He is an active member of the American College of Cardiology, the Florida Chapter of the American College of Cardiology, the American Heart Association, and the Society of Coronary Angiography and Intervention.