Peripheral intravenous line - infants


A peripheral intravenous line (PIV) is a small, short, plastic tube, called a catheter. A health care provider puts the PIV through the skin into a vein in the scalp, hand, arm, or foot. This article addresses PIVs in babies.

Alternative Names

PIV - infants; Peripheral IV - infants; Peripheral line - infants; Peripheral line - neonatal



A provider uses the PIV to give fluids or medicines to a baby.


Your provider will:

  • Clean the skin.
  • Stick the small catheter with a needle on the end through the skin into the vein.
  • Once the PIV is in the proper position, the needle is taken out. The catheter stays in the vein.
  • The PIV is connected to a small plastic tube that connects to an IV bag.


PIVs can be hard to place in a baby, such as when a baby is very chubby, sick, or small. In some cases, the provider cannot put in a PIV. If this happens, another therapy is needed.

PIVs may stop working after only a short time. If this happens, the PIV will be taken out and a new one will be put in.

If a PIV slips out of the vein, fluid from the IV can go into the skin instead of the vein. When this happens, the IV is considered "infiltrated." The IV site will look puffy and may be red. Sometimes, an infiltrate may cause the skin and tissue to get very irritated. The baby can get a tissue burn if the medicine that was in the IV is irritating to the skin. In some special cases, medicines may be injected into the skin to reduce the risk for long-term skin damage from an infiltrate.

When a baby needs IV fluids or medicine over a long period of time, a midline catheter or PICC is used. Regular IVs only last 1 to 3 days before needing to be replaced. A midline or PICC can stay in for 2 to 3 weeks or longer.


Peripheral intravenous line


Center of Disease Control and Prevention website. Guidelines for the prevention of intravascular catheter-related infections, 2011. Accessed September 26, 2019.

Said MM, Rais-Bahrami K. Peripheral intravenous line placement. In: MacDonald MG, Ramasethu J, Rais-Bahrami K, eds. Atlas of Procedures in Neonatology. 5th ed. Philadelphia, PA: Wolters Kluwer/Lippincott Williams & Wilkins; 2012:chap 27.

Santillanes G, Claudius I. Pediatric vascular access and blood sampling techniques. In: Roberts J, ed. Roberts and Hedges' Clinical Procedures in Emergency Medicine and Acute Care. 7th ed. Philadelphia, PA: Elsevier Saunders; 2019:chap 19.

Review Date: 
Reviewed By: 
Kimberly G. Lee, MD, MSc, IBCLC, Clinical Professor of Pediatrics, Division of Neonatology, Medical University of South Carolina, Charleston, SC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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