Chronic: Research Studies

33 Related Result(s)

  1. Chronic Kidney Disease in Children (CKID)

    The purpose of this study is to investigate what factors make chronic kidney disease worse in children and to see how CKID affects a child's brain...

  2. A Clinical Study to Demonstrate Safety and Efficacy of E7777 (Denileukin Diftitox) in Persistent or Recurrent Cutaneous T-Cell Lymphoma

    The purpose of this trial is to assess the efficacy and safety of E7777 (improved purity ONTAK [denileukin diftitox]) in patients with persistent and...

  3. HCV-Target: Hepatitis C Therapeutic Registry And Research Network-A Longitudinal, Observational Study

    The purpose of this study is to collect and study information on patients with chronic Hepatitis C Virus (HCV) who are being treated with the protease...

  4. Phase III Randomized, Placebo-Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy +/- One Year of Everolimus in Patients with High-Risk, Hormone Receptor-Positive and HER2/neu Negative Breast Cancer . e3 Breast Cancer Study - evaluating everolimus with endocrine therapy

    This randomized phase III trial studies how well aspirin works in preventing the cancer from coming back (recurrence) in patients with human epidermal growth...

  5. A Phase II Study to Assess the Activity of PD-L Inhibition with Durvalumab (MEDI4736) after Chemo-Radiotherapy in Patients with Stage II-IV Microsatellite Stable (MSS) Rectal Cancer

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  6. A Phase 1/2A Open-Label, Multi-Dose, Multi-Center Escalation and Exploratory Study of Cerdulatinib (PRT062070) in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) or B Cell or T Cell Non-Hodgkin Lymphoma (NHL)

    The primary objective is to determine the maximum tolerated dose/ maximum administered dose of cerdulatinib in patients with relapsed/refractory chronic...

  7. Breast Cancer Lung Late Effects (BELLE)

    This study will use CT imaging, pulmonary function tests, and blood samples to examine the differences in pulmonary vessel radiation damage between patients...

  8. A Phase III, International, Randomized, Controlled Study of Rigosertib versus Physician's Choice of Treatment in Patients with Myelodysplastic Syndrome after Failure of a Hypomethylating Agent

    The primary objective of this study is to compare the overall survival (OS) of patients receiving intravenous (IV) rigosertib to the OS of patients receiving...

  9. Central Mechanisms of Chronic Pain and Fatigue: Functional Imaging of Brain and Spinal Cord

    The purpose of this research study is to evaluate the changes in brain and spinal cord activity that can occur with the feeling of painful experimental...

  10. Blood Flow Restriction Exercise for Older Adults Undergoing Knee Replacement Surgery

    This pilot study will investigate the effects of blood flow restriction (BFR) exercise for up to 4 -6 weeks prior TKA surgery in older patients to determine...

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