Melanoma: Research Studies

8 Related Result(s)

  1. (2-THE-TOP) Phase 2, Single Arm, Historically Controlled Study Testing The Safety and Efficacy of Adjuvant Temozolomide Plus TTFields (Optune®) Plus Pembrolizumab in Patients with Newly Diagnosed Glioblastoma

    Glioblastoma multiforme (GBM) is the most common and deadliest primary malignant neoplasm of the central nervous system in adults. Despite an aggressive...

  2. A Phase II Study to Assess the Activity of PD-L Inhibition with Durvalumab (MEDI4736) after Chemo-Radiotherapy in Patients with Stage II-IV Microsatellite Stable (MSS) Rectal Cancer

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  3. A Phase II Trial of TAS-102 (Lonsurf) in Patients With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma After Progression Through First Line Chemotherapy

    The primary objective is to evaluate the activity of TAS-102 in previously treated metastatic and locally...

  4. PAN009-18 (PC04): A Phase II Trial of Escalated Dose Proton Radiotherapy with Elective Nodal Irradiation and Concomitant Chemotherapy for Patients with Unresectable, Borderline Resectable or Medically inoperable Pancreatic Adenocarcinoma

    The prognosis for patients with localized pancreatic adenocarcinoma who are not surgical candidates is poor. Patients characterized as having "borderline...

  5. Phase II Trial of Niraparib in BAP1 and other DDR Deficient Neoplasms (UF-STO-ETI-001)

    The purpose of this study is to investigate the use of niraparib in patients with tumors known to have mutations in BAP1 and other select DNA damage...

  6. Phase II Trial of the PARP1 Inhibitor, Niraparib, in BAP1 and other DNA Damage Response (DDR) Pathway Deficient Neoplasms

    The primary objective is to determine the response rate for subject with mutations in BAP1 and other genes...

  7. Targeted Therapy Directed by Genetic Testing in Advanced Refractory Solid Tumors or Lymphomas

    This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have...

  8. TORCH Clinical Trial

    Thank you for your interest in research at the University of Florida. ...