Neuromedicine Specialties: Neurovascular Surgery
The neurovascular program at UF Health Shands Hospital is one of the leading programs in the nation for comprehensive cerebrovascular and endovascular neurosurgery.
Under the direction of Brian Hoh, M.D., the team performs hundreds of procedures annually, including endovascular and open cerebrovascular surgery to treat many of the most complex neurovascular disorders.
The University of Florida neurovascular team performs many of the latest endovascular neurosurgical procedures using image-guidance technology for both diagnosis and treatment.
The UF neurovascular team performs hundreds of procedures every year. These include:
- Aneurysm clipping
- Balloon angioplasty
- Carotid endarterectomy
- Coiling of aneurysms
- Combination cerebrovascular/endovascular procedures
- Diagnostic angiography
- EC-IC bypass for complex aneurysm, ischemic stroke and Moya Moya disease
- Embolization of arteriovenous malformations
- Embolization of tumors
- Embolization of vein of Galen malformations and other pediatric neurovascular procedures
- Endovascular treatment of acute strokes
- Intracranial and extracranial angioplasty and stent placement
- Obliteration of arteriovenous fistulae
- Resection of intracranial arteriovenous malformations
- Resection of spinal arteriovenous malformations
- Vertebroplasty or kyphoplasty for spinal compression fractures
The team actively participates in many cerebrovascular/endovascular clinical trials where the latest high-technology devices are constantly being evaluated and perfected for improved patient care. An active research laboratory focuses on prevention and treatment of stroke, intracranial aneurysms and arteriovenous malformations.
UF is an active participation site for many cerebrovascular endovascular clinical trials. The latest technological advances are constantly being evaluated and perfected for enhanced patient care.
Researchers in Dr. Hoh's laboratory investigate the role of hematopoietic stem cells and endothelial progenitor cells in cerebrovascular disease, specifically carotid atherosclerosis, aneurysm formation, aneurysm recanalization after coil embolization and stroke. Dr. Hoh works closely with the University of Florida Program in Stem Cell Biology and Regenerative Medicine, studying the mechanisms by which aneurysms form in order to eventually develop therapies for treating or preventing aneurysms.
The neurovascular surgery team also operates the neurovascular-neurotrauma lab. The team has developed a clinical platform to investigate proteomics and their potential use in acute brain injury. In addition, the lab is involved in NIH-funded work in collaboration with other academic medical centers.
Numerous studies are also underway in the area of cerebrovascular surgery. Among them is research into proteomics and biomarkers in acute brain injury from aneurysmal subarachnoid hemorrhage to determine if specific biomarkers can be used to define specific events occurring in the injured brain.