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Necrotizing granuloma

Definition

A granuloma is a clump of cells that forms when the immune system tries to fight off a harmful substance but cannot remove it from the body.

A necrotizing granuloma is an area of inflammation in which tissue has died. Necrotizing means dying or decaying.

Tuberculosis and granulomatosis with polyangiitis are conditions that cause necrotizing granulomas.

Alternative Names

Granuloma

References

Jones KD, Urisman A. Histopathologic approach to the surgical lung biopsy in interstitial lung disease. In: Collard HR, Richeldi L, eds. Interstitial Lung Disease. Philadelphia, PA: Elsevier; 2018:chap 12.

Last reviewed September 19, 2021 by Debra G. Wechter, MD, FACS, General Surgery Practice Specializing in Breast Cancer, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team..

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