Nam H Dang, M.D., Ph.D.
(352) 265-0725
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Publications
Successful Surgical Removal of the Largest Known Spleen.
Case reports in surgery
2020
Single-institution Retrospective Analysis of Prognostic Factors Influencing Very Late-onset Post-transplant Lymphoproliferative Disorder.
Cureus
2020
Reduction of immunosuppression for post-transplant lymphoproliferative disorder (PTLD): a single-center experience of allograft survival outcomes.
Leukemia & lymphoma
2020
Post Transplant Lymphoproliferative Disorder risk factors in children: Analysis of a 23-year single-institutional experience.
Pediatric transplantation
2020
Intravascular Large B-Cell Lymphoma Presenting as Acute Axonal Polyneuropathy: A Case Report and Literature Review.
Journal of investigative medicine high impact case reports
2020
Impact of DPP4 Inhibitors in Survival of Patients With Prostate, Pancreas, and Breast Cancer.
Frontiers in oncology
2020
Bilateral pseudohypopyon causing white eyes in a patient with lymphoma.
Lancet (London, England)
2020
Rheumatic diseases associated with immune checkpoint inhibitors in cancer immunotherapy.
Modern rheumatology
2019
Ibrutinib plus lenalidomide and rituximab has promising activity in relapsed/refractory non-germinal center B-cell-like DLBCL.
Blood
2019
Dipeptidyl peptidase 4 inhibitors as novel agents in improving survival in diabetic patients with colorectal cancer and lung cancer: A Surveillance Epidemiology and Endpoint Research Medicare study.
Cancer medicine
2019
Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens.
PloS one
2019
DPP8 is a novel therapeutic target for multiple myeloma.
Scientific reports
2019
Characterization of novel anti-IL-26 neutralizing monoclonal antibodies for the treatment of inflammatory diseases including psoriasis.
mAbs
2019
Biological Effects of IL-26 on T Cell-Mediated Skin Inflammation, Including Psoriasis.
The Journal of investigative dermatology
2019
A multi-center retrospective analysis of the effect of DPP4 inhibitors on progression-free survival in advanced airway and colorectal cancers.
Molecular and clinical oncology
2019
Targeting CD26 suppresses proliferation of malignant mesothelioma cell via downmodulation of ubiquitin-specific protease 22.
Biochemical and biophysical research communications
2018
Randomized, phase 3 trial of inotuzumab ozogamicin plus rituximab versus chemotherapy plus rituximab for relapsed/refractory aggressive B-cell non-Hodgkin lymphoma.
British journal of haematology
2018
A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target.
Frontiers in bioscience (Landmark edition)
2018
A novel role for CD26/dipeptidyl peptidase IV as a therapeutic target.
Frontiers in bioscience (Landmark edition)
2018
Post-transplant lymphoproliferative disorder (PTLD): single institutional experience of 141 patients.
Experimental hematology & oncology
2017
Phase 1 study of inotuzumab ozogamicin combined with R-GDP for the treatment of patients with relapsed/refractory CD22+ B-cell non-Hodgkin lymphoma.
Journal of drug assessment
2017
First-in-human phase 1 of YS110, a monoclonal antibody directed against CD26 in advanced CD26-expressing cancers.
British journal of cancer
2017
A possible role for CD26/DPPIV enzyme activity in the regulation of psoriatic pruritus.
Journal of dermatological science
2017
Role of IL-26+CD26+CD4 T Cells in Pulmonary Chronic Graft-Versus-Host Disease and Treatment with Caveolin-1-Ig Fc Conjugate.
Critical reviews in immunology
2016
Multidimensional Screening Platform for Simultaneously Targeting Oncogenic KRAS and Hypoxia-Inducible Factors Pathways in Colorectal Cancer.
ACS chemical biology
2016
Low Grade Lymphoma Mimicking Metastatic Urothelial Carcinoma: When Do We Need Further Histologic Staging?
Case reports in oncological medicine
2016
Inhibition of VEGF-dependent angiogenesis by the anti-CD82 monoclonal antibody 4F9 through regulation of lipid raft microdomains.
Biochemical and biophysical research communications
2016
Disparities in conditional net survival among non-Hodgkin lymphoma survivors: a population-based analysis.
Leukemia & lymphoma
2016
A Novel Case of Penile Gangrene in a Patient Treated with Ibrutinib for Chronic Lymphocytic Leukemia.
Case reports in oncological medicine
2016
The role of Cas-L/NEDD9 as a regulator of collagen-induced arthritis in a murine model.
Biochemical and biophysical research communications
2015
Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
2015
Phase 1/2 study of ocaratuzumab, an Fc-engineered humanized anti-CD20 monoclonal antibody, in low-affinity FcγRIIIa patients with previously treated follicular lymphoma.
Leukemia & lymphoma
2015
New primary malignancy masquerading as metastatic prostate adenocarcinoma.
Case reports in oncological medicine
2015
Modulation of immunological responses and amelioration of collagen-induced arthritis by the novel roxithromycin derivative 5-I.
Modern rheumatology
2015
Denileukin Diftitox (Ontak) as Maintenance Therapy for Peripheral T-Cell Lymphomas: Three Cases with Sustained Remission.
Case reports in oncological medicine
2015
Comparison of two commercial ELISAs against an in-house ELISA for measuring soluble CD26 in human serum.
Journal of clinical laboratory analysis
2015
CD26-mediated induction of EGR2 and IL-10 as potential regulatory mechanism for CD26 costimulatory pathway.
Journal of immunology (Baltimore, Md. : 1950)
2015
Regulation of Somatostatin Receptor 4-Mediated Cytostatic Effects By Cd26 in Malignant Pleural Mesothelioma
British journal of cancer
2014
Paclitaxel, topotecan and rituximab: long term outcomes of an effective salvage programme for relapsed or refractory aggressive B-cell non-Hodgkin lymphoma.
British journal of haematology
2014
Involved-node proton therapy in combined modality therapy for Hodgkin lymphoma: results of a phase 2 study.
International journal of radiation oncology, biology, physics
2014
Establishment of monoclonal anti-human CD26 antibodies suitable for immunostaining of formalin-fixed tissue.
Diagnostic pathology
2014
CD9 negatively regulates CD26 expression and inhibits CD26-mediated enhancement of invasive potential of malignant mesothelioma cells.
PloS one
2014
CD26-mediated regulation of periostin expression contributes to migration and invasion of malignant pleural mesothelioma cells.
Biochemical and biophysical research communications
2014
ALK1 as a novel therapeutic target for CD30⁺ T-anaplastic large cell lymphoma.
Journal of the National Cancer Institute
2014
The role of monoclonal antibodies in the treatment of lymphomas.
Expert opinion on biological therapy
2013
Survey of the University of Florida Hematology/Oncology Fellows On Perceived Skills of Independent Management of Oncologic Pain, Chemotherapy-Related Nausea and Vomiting, and End-Of-Life Discussions
Journal of Clinical Oncology
2013
Safety and clinical activity of a combination therapy comprising two antibody-based targeting agents for the treatment of non-Hodgkin lymphoma: results of a phase I/II study evaluating the immunoconjugate inotuzumab ozogamicin with rituximab.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2013
Prevention of acute graft-versus-host disease by humanized anti-CD26 monoclonal antibody.
British journal of haematology
2013
Polyarthropathy in type 2 diabetes patients treated with DPP4 inhibitors.
Diabetes research and clinical practice
2013
Phase 2 Study of Consolidative Involved-Node Proton Therapy in Patients With Hodgkin Lymphoma: Early Outcomes
International Journal of Radiation Oncology Biology Physics
2013
Long term results of a phase 2 study of vincristine sulfate liposome injection (Marqibo(®) ) substituted for non-liposomal vincristine in cyclophosphamide, doxorubicin, vincristine, prednisone with or without rituximab for patients with untreated aggressive non-Hodgkin lymphomas.
British journal of haematology
2013
Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody.
Journal of virology
2013
CD26-mediated co-stimulation in human CD8(+) T cells provokes effector function via pro-inflammatory cytokine production.
Immunology
2013
CD26 expression on T-anaplastic large cell lymphoma (ALCL) line Karpas 299 is associated with increased expression of versican and MT1-MMP and enhanced adhesion.
BMC cancer
2013
Systemic Capillary Leak Syndrome as an Initial Presentation of ALK-Negative Anaplastic Large Cell Lymphoma.
Case reports in hematology
2012
Results of a Phase 1 Study of Ame-133V (Ly2469298), An Fc-Engineered Humanized Monoclonal Anti-Cd20 Antibody, in Fc Gamma Riiia-Genotyped Patients With Previously Treated Follicular Lymphoma
Clinical Cancer Research
2012
Impact of the integrin signaling adaptor protein NEDD9 on prognosis and metastatic behavior of human lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research
2012
Effective dose reduction to cardiac structures using protons compared with 3DCRT and IMRT in mediastinal Hodgkin lymphoma.
International journal of radiation oncology, biology, physics
2012
Consolidative involved-node proton therapy for Stage IA-IIIB mediastinal Hodgkin lymphoma: preliminary dosimetric outcomes from a Phase II study.
International journal of radiation oncology, biology, physics
2012
Characterization of cancer stem cell properties of CD24 and CD26-positive human malignant mesothelioma cells.
Biochemical and biophysical research communications
2012
Characterization of Cancer Stem Cell Properties of Cd24 and Cd26-Positive Human Malignant Mesothelioma Cells (Vol 419, Pg 529, 2012)
Biochemical and Biophysical Research Communications
2012
CD26 overexpression is associated with prolonged survival and enhanced chemosensitivity in malignant pleural mesothelioma.
Clinical cancer research : an official journal of the American Association for Cancer Research
2012
Anti-Tumor Activity of Low Dose Ocaratuzumab in Previously Treated Follicular Lymphoma Patients With Low-Affinity Cd16 Polymorphisms
Blood
2012
Advantages of Proton Therapy in the Management of Primary Mediastinal B-Cell Lymphoma (Pmbcl)
British Journal of Haematology
2012
Reducing the Dose To the Cardiac Chambers, Valves, and Vessels With Proton Therapy Compared With 3D-Crt and Imrt in Patients With Mediastinal Hodgkin Lymphoma
International Journal of Radiation Oncology Biology Physics
2011
Mechanisms of confluence-dependent expression of CD26 in colon cancer cell lines.
BMC cancer
2011
Dipeptidyl peptidase in autoimmune pathophysiology.
Advances in clinical chemistry
2011
Combination therapy for renal cell cancer: what are possible options?
Oncology
2011
A New Derivative of Roxithromycin Modulates Immunological Responses and Ameliorates Collagen-Induced Arthritis
Arthritis and Rheumatism
2011
Inhibition of dipeptidyl peptidase 4 regulates microvascular endothelial growth induced by inflammatory cytokines.
Biochemical and biophysical research communications
2010
Aqueous extract of Carica papaya leaves exhibits anti-tumor activity and immunomodulatory effects.
Journal of ethnopharmacology
2010
Anti-Cd22 Immunoconjugate Inotuzumab Ozogamicin (Cmc-544) + Rituximab: Clinical Activity in Patients With Relapsed/Refractory Follicular Or `Aggressive' Lymphoma
Haematologica
2010
SHP-2 inhibits tyrosine phosphorylation of Cas-L and regulates cell migration.
Biochemical and biophysical research communications
2009
CD90 and CD110 correlate with cancer stem cell potentials in human T-acute lymphoblastic leukemia cells.
Biochemical and biophysical research communications
2009
CD9 correlates with cancer stem cell potentials in human B-acute lymphoblastic leukemia cells.
Biochemical and biophysical research communications
2009
CD26 expression on T cell lines increases SDF-1-alpha-mediated invasion.
British journal of cancer
2009
Blockade of CD26-mediated T cell costimulation with soluble caveolin-1-Ig fusion protein induces anergy in CD4+T cells.
Biochemical and biophysical research communications
2009
Anti-Cd22 Immunoconjugate Inotuzumab Ozogamicin (Cmc-544) + Rituximab: Clinical Activity Including Survival in Patients With Recurrent/Refractory Follicular Or `Aggressive' Lymphoma
Blood
2009
The role of CD26/dipeptidyl peptidase IV in cancer.
Frontiers in bioscience : a journal and virtual library
2008
Role of CD26/dipeptidyl peptidase IV in human T cell activation and function.
Frontiers in bioscience : a journal and virtual library
2008
Revisiting an old acquaintance: CD26 and its molecular mechanisms in T cell function.
Trends in immunology
2008
Hypoxia-inducible factor-1 target genes as indicators of tumor vessel response to vascular endothelial growth factor inhibition.
Cancer research
2008
De novo maintenance therapy with denileukin diftitox (Ontak) in a patient with peripheral T-cell lymphoma is associated with prolonged remission.
American journal of hematology
2008
Comparative study of regulatory T cell function of human CD25CD4 T cells from thymocytes, cord blood, and adult peripheral blood.
Clinical & developmental immunology
2008
Stem cell properties and the side population cells as a target for interferon-alpha in adult T-cell leukemia/lymphoma.
Biochemical and biophysical research communications
2007
Phase II trial of the combination of denileukin diftitox and rituximab for relapsed/refractory B-cell non-Hodgkin lymphoma.
British journal of haematology
2007
Phase II trial of denileukin diftitox for relapsed/refractory T-cell non-Hodgkin lymphoma.
British journal of haematology
2007
Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells.
Cancer research
2007
Humanized anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research
2007
Denileukin diftitox as novel targeted therapy for lymphoid malignancies.
Cancer investigation
2007
Caveolin-1 triggers T-cell activation via CD26 in association with CARMA1.
The Journal of biological chemistry
2007
CD26/dipeptidyl peptidase IV as a novel therapeutic target for cancer and immune disorders.
Mini reviews in medicinal chemistry
2007
T-cell activation via CD26 and caveolin-1 in rheumatoid synovium.
Modern rheumatology
2006
Anti-CD26 monoclonal antibody-mediated G1-S arrest of human renal clear cell carcinoma Caki-2 is associated with retinoblastoma substrate dephosphorylation, cyclin-dependent kinase 2 reduction, p27(kip1) enhancement, and disruption of binding to the extracellular matrix.
Clinical cancer research : an official journal of the American Association for Cancer Research
2006
Toxic epidermal necrolysis associated with denileukin diftitox (DAB389IL-2) administration in a patient with follicular large cell lymphoma.
Leukemia & lymphoma
2005
Roxithromycin specifically inhibits development of collagen induced arthritis and production of proinflammatory cytokines by human T cells and macrophages.
The Journal of rheumatology
2005
Regulation of p38 phosphorylation and topoisomerase IIalpha expression in the B-cell lymphoma line Jiyoye by CD26/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin.
Cancer research
2005
Prognostic factors and treatment of patients with T-cell non-Hodgkin lymphoma: the M. D. Anderson Cancer Center experience.
Cancer
2005
Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2005
Nedd9 protein, a Cas-L homologue, is upregulated after transient global ischemia in rats: possible involvement of Nedd9 in the differentiation of neurons after ischemia.
Stroke
2005
High rate of durable remissions after treatment of newly diagnosed aggressive mantle-cell lymphoma with rituximab plus hyper-CVAD alternating with rituximab plus high-dose methotrexate and cytarabine.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2005
HTLV-I Tax induces and associates with Crk-associated substrate lymphocyte type (Cas-L).
Oncogene
2005
CD26 regulates p38 mitogen-activated protein kinase-dependent phosphorylation of integrin beta1, adhesion to extracellular matrix, and tumorigenicity of T-anaplastic large cell lymphoma Karpas 299.
Cancer research
2005
CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells.
Molecular and cellular biology
2005
Phase II study of denileukin diftitox for relapsed/refractory B-Cell non-Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2004
Phase II clinical trial of interleukin-12 in patients with relapsed and refractory non-Hodgkin's lymphoma and Hodgkin's disease.
Clinical cancer research : an official journal of the American Association for Cancer Research
2004
Denileukin diftitox as novel targeted therapy in non-Hodgkin's lymphoma.
Clinical journal of oncology nursing
2004
CD26 up-regulates expression of CD86 on antigen-presenting cells by means of caveolin-1.
Proceedings of the National Academy of Sciences of the United States of America
2004
Association of CD26 with CD45RA outside lipid rafts attenuates cord blood T-cell activation.
Blood
2004
T-large granular lymphocyte lymphoproliferative disorder: expression of CD26 as a marker of clinically aggressive disease and characterization of marrow inhibition.
British journal of haematology
2003
SS-A/Ro52, an autoantigen involved in CD28-mediated IL-2 production.
Journal of immunology (Baltimore, Md. : 1950)
2003
Pentostatin in T-non-Hodgkin's lymphomas: efficacy and effect on CD26+ T lymphocytes.
Oncology reports
2003
CD26: a novel treatment target for T-cell lymphoid malignancies? (Review).
International journal of oncology
2003
CD26: a key molecule in immune regulation and autoimmune diseases.
Modern rheumatology
2003
Soluble CD26/dipeptidyl peptidase IV enhances transendothelial migration via its interaction with mannose 6-phosphate/insulin-like growth factor II receptor.
Cellular immunology
2002
G1/S cell cycle arrest provoked in human T cells by antibody to CD26.
Immunology
2002
Research Interests