N Edwards, M.D.

N L Edwards, M.D.

(352) 265-0239

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Publications

Response to the 2020 American College of Rheumatology Guideline for the Management of Gout: Comment on the Article by FitzGerald et al.
Arthritis care & research
2020

Management of Gout in the United States: A Claims-based Analysis.
ACR open rheumatology
2020

Gout management and outcomes during the COVID-19 pandemic: a cross-sectional internet survey
Therapeutic advances in musculoskeletal disease.
2020

Development of a multivariable improvement measure for gout.
Arthritis research & therapy
2020

Patient Perceptions of Gout Management Goals: A Cross-sectional Internet Survey.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
2019

Gout, Hyperuricemia, and Crystal-Associated Disease Network Consensus Statement Regarding Labels and Definitions for Disease Elements in Gout.
Arthritis care & research
2019

Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-CAN) consensus statement regarding labels and definitions of disease states of gout.
Annals of the rheumatic diseases
2019

Experience of finding footwear and factors contributing to footwear choice in people with gout: a mixed methods study using a web-based survey.
Journal of foot and ankle research
2019

Evaluation of Proposed Criteria for Remission and Evidence-Based Development of Criteria for Complete Response in Patients With Chronic Refractory Gout.
ACR open rheumatology
2019

EULAR gout treatment guidelines by Richette et al.: uric acid and neurocognition.
Annals of the rheumatic diseases
2018

Renal dosing of allopurinol results in suboptimal gout care.
Annals of the rheumatic diseases
2017

Overview of Serum Uric Acid Treatment Targets in Gout: Why Less Than 6 mg/dL?
Postgraduate medicine
2016

A cross-sectional internet-based patient survey of the management strategies for gout.
BMC complementary and alternative medicine
2016

An internet survey of common treatments used by patients with gout including cherry extract and juice and other dietary supplements.
Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
2015

2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative.
Annals of the rheumatic diseases
2015

2015 Gout Classification Criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative.
Arthritis & rheumatology (Hoboken, N.J.)
2015

OMERACT endorsement of measures of outcome for studies of acute gout.
The Journal of rheumatology
2014

Emerging therapies for gout.
Rheumatic diseases clinics of North America
2014

Application of the OMERACT filter to measures of core outcome domains in recent clinical studies of acute gout.
The Journal of rheumatology
2014

A Delphi Exercise To Identify Characteristic Features of Gout - Opinions From Patients and Physicians, the First Stage in Developing New Classification Criteria
The Journal of rheumatology
2013

Improved health-related quality of life and physical function in patients with refractory chronic gout following treatment with pegloticase: evidence from phase III randomized controlled trials.
The Journal of rheumatology
2012

2012 American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis.
Arthritis care & research
2012

2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia.
Arthritis care & research
2012

Work productivity loss due to flares in patients with chronic gout refractory to conventional therapy.
Journal of medical economics
2011

Tophus measurement as an outcome measure for clinical trials of chronic gout: progress and research priorities.
The Journal of rheumatology
2011

Serum urate in chronic gout--will it be the first validated soluble biomarker in rheumatology?
The Journal of rheumatology
2011

Serum urate as a soluble biomarker in chronic gout-evidence that serum urate fulfills the OMERACT validation criteria for soluble biomarkers.
Seminars in arthritis and rheumatism
2011

Quality of care in patients with gout: why is management suboptimal and what can be done about it?
Current rheumatology reports
2011

Patient-reported outcomes in chronic gout: a report from OMERACT 10.
The Journal of rheumatology
2011

Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials.
JAMA
2011

Bringing it all together: a novel approach to the development of response criteria for chronic gout clinical trials.
The Journal of rheumatology
2011

2011 recommendations for the diagnosis and management of gout and hyperuricemia.
The Physician and sportsmedicine
2011

2011 Recommendations for the diagnosis and management of gout and hyperuricemia.
Postgraduate medicine
2011

Preventing and treating acute gout attacks across the clinical spectrum: a roundtable discussion.
Cleveland Clinic journal of medicine
2010

Managing gout in the primary care setting: what you and your patients need to know.
The American journal of medicine
2010

Chronic Gout: Epidemiology, Disease Progression, Treatment and Disease Burden
Current Medical Research and Opinion
2010

Toward a valid definition of gout flare: results of consensus exercises using Delphi methodology and cognitive mapping.
Arthritis and rheumatism
2009

The role of hyperuricemia in vascular disorders.
Current opinion in rheumatology
2009

Progress in measurement instruments for acute and chronic gout studies.
The Journal of rheumatology
2009

Outcome Domains for Studies of Acute and Chronic Gout
The Journal of rheumatology
2009

Gout. Hyperuricemia and cardiovascular disease: how strong is the evidence for a causal link?
Arthritis research & therapy
2009

Febuxostat: a new treatment for hyperuricaemia in gout.
Rheumatology (Oxford, England)
2009

Work Productivity Loss Due To Flares in Treatment-Failure Gout (Tfg)
Arthritis and Rheumatism
2008

Treatment-failure gout: a moving target.
Arthritis and rheumatism
2008

The role of hyperuricemia and gout in kidney and cardiovascular disease.
Cleveland Clinic journal of medicine
2008

In defense of research into the crystal induced arthropathies.
The Journal of rheumatology
2008

Improvement in Health-Related Quality of Life (Hrql) and Disability Index in Treatment Failure Gout (Tfg) After Pegloticase (Pgl) Therapy: Pooled Results From Gout1 and Gout2, Phase 3, Randomized Double Blind, Placebo (Pbo)-Controlled Trials
Arthritis and Rheumatism
2008

Immunoreactivity and Clinical Response To Pegloticase (Pgl): Pooled Data From Gout1 and Gout2, Pgl Phase 3 Randomized, Double Blind, Placebo-Controlled Trials
Arthritis and Rheumatism
2008

Immunoreactivity and Clinical Response To Pegloticase (Pgl): Pooled Data From Gout1 and Gout2, Pgl Phase 3 Randomized, Double Blind, Placebo-Controlled Trials
Arthritis and Rheumatism
2008

Health-Related Quality-Of-Life (Hrqol) of Patients With Refractory Gout (Refractory-Gout) and Us Veterans Administration Patients With Gout and Comorbities (Va-Gout) Is Poor and Comparable To That in Other Severe Chronic Conditions
Arthritis and Rheumatism
2008

Febuxostat : a viewpoint by N. Lawrence Edwards.
Drugs
2008

Febuxostat - a Viewpoint
Annals of epidemiology
2008

Efficacy and Safety of Intravenous (Iv) Pegloticase (Pgl) in Subjects With Treatment Failure Gout (Tfg): Phase 3 Results From Gout1 and Gout2
Arthritis and Rheumatism
2008

Clinical Homogeneity and Syndromic Characteristics of Treatment Failure Gout (Tfg) in Four Independent Cohorts
Arthritis and Rheumatism
2008

Outcome evaluations in gout.
The Journal of rheumatology
2007

Magnetic resonance imaging in the quantitative assessment of gouty tophi.
International journal of clinical practice
2006

Case 9: initiation of urate-lowering therapy for advanced gout complicated by chronic renal insufficiency.
The American journal of medicine
2006

Case 7: differential diagnosis of advanced gout.
The American journal of medicine
2006

Case 6: maintenance therapy for simple intermittent gout.
The American journal of medicine
2006

Treatment of osteoarthritis.
Southern medical journal
2005

Magnetic resonance imaging of tophaceous gout in the hands and wrists.
Seminars in arthritis and rheumatism
1996

New insights into gouty arthritis.
Contemporary internal medicine
1995

Clinical pathogenesis and diagnosis of osteoarthritis.
Contemporary internal medicine
1995

Axial skeletal changes in paralysed patients may mimic ankylosing spondylitis.
British journal of rheumatology
1995

A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.
The EMBO journal
1993

Drugs to lower uric acid levels. How to avoid misuse in gouty arthritis.
Postgraduate medicine
1991

Magnetic resonance imaging in patients with inflammatory arthritis of the knee.
Clinical rheumatology
1990

Profile of a meeting: how abstracts are written and reviewed.
The Journal of rheumatology
1989

Metabolism of guanosine and its C-8 substituted analogues in human lymphocyte cytoplasm.
Advances in experimental medicine and biology
1989

Cerebrospinal fluid cyclic nucleotide alterations in the Lesch-Nyhan syndrome.
Advances in experimental medicine and biology
1989

Vasculitis associated with malignancy. Experience with 13 patients and literature review.
Medicine
1988

'Rhupus' syndrome.
Archives of internal medicine
1988

Technetium pyrophosphate muscle scans in inflammatory muscle disease.
British journal of rheumatology
1987

Silicone and rheumatic diseases.
Seminars in arthritis and rheumatism
1987

Central nervous system vasculitis.
Annals of allergy
1987

The effect of allopurinol on cerebral spinal fluid (CSF) purines in hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency syndromes.
Advances in experimental medicine and biology
1986

Purine and monoamine metabolites in cerebrospinal fluid.
Advances in experimental medicine and biology
1986

Is running associated with degenerative joint disease?
JAMA
1986

Lesch-Nyhan syndrome: CSF neurotransmitter abnormalities.
Neurology
1985

Plasma membrane 5'-nucleotidase and other purine enzymes in murine lymphocytes.
Advances in experimental medicine and biology
1984

Enzyme replacement in the Lesch-Nyhan syndrome with long-term erythrocyte transfusions.
Advances in experimental medicine and biology
1984

The diagnosis and management of gouty arthritis.
Comprehensive therapy
1983

Hypoxanthine salvage in man: its importance in urate overproduction in the Lesch-Nyhan syndrome.
Advances in experimental medicine and biology
1980

Altered purine and pyrimidine metabolism in erythrocytes with purine nucleoside phosphorylase deficiency.
Biochemical genetics
1980

Overproduction of uric acid in hypoxanthine-guanine phosphoribosyltransferase deficiency. Contribution by impaired purine salvage.
The Journal of clinical investigation
1979