UF Health Neurosurgery is one of the leading programs in the nation for cerebrovascular and endovascular neurosurgery. UF Health cerebrovascular/endovascular neurosurgeons can perform a variety of procedures. The team provides specialized, state-of the-art care to patients with neurovascular conditions; care that is both timely and compassionate.
The UF Health cerebrovascular/endovascular team performs more than 1,000 procedures every year, including both endovascular and open cerebrovascular surgeries to treat the most complex neurovascular disorders. They are pioneers in advancing the treatment of neurovascular disease through clinical and basic science research, and through developing, testing and refining the latest technologies and devices to improve patient care.
About Moyamoya Disease
Moyamoya disease is a progressive disease of the proximal cerebral blood vessels. It is characterized by narrowing of the internal carotid artery, middle cerebral artery, and anterior cerebral artery. The condition leads to irreversible blockage of the main blood vessels to the brain as they enter into the skull.
Moyamoya tends to affect children, as well as adults in the third to fourth decades of life. Children present with symptoms of stroke, such as weakness of an arm or leg, or seizures. Adults tend to present with ischemic or hemorrhagic stroke.
Signs and Symptoms
Patients tend to present with signs of stroke or mini-strokes. They complain of speech difficulties, paralysis of part of the body, weakness, numbness, or loss of conciousness. Symptoms can be permenant or transient.
Diagnosis of Moyamoya
The diagnosis is made by any neuroimaging study that evaluates blood vessels.
|Formal angiography of the cerebral vessels is the most accurate.||CT-angiogram and MR-angiogram can make the diagnosis as well.|
MRI with diffusion weighting is the best study to evaluate for evidence of strokes. Often nuclear medicine studies such as SPECT (single photon emission computerized tomography) or a DIAMOX nuclear medicine scan are used to demonstrate the decreased blood and oxygen supply to areas of the brain involved with the Moyamoya disease.
Treatment of Moyamoya Disease
The initial therapy for Moyamoya consists of blood thinning therapy, usually asprin. This helps blood travel through the narrowed intracranial blood vessels. Most patients are followed regularly and have repeat imaging to evaluate any changes in blood vessel size. Surgery is indicated if there are worsening symptoms. The 2 surgical treatments that we offer are:
- Direct revascularization (STA to MCA bypass), which involves actually joining the superficial temporal artery to a blood vessel on the surface of the brain (see EC-IC bypass).
- Indirect revascularization (EDAS procedure); an on-lay revascularization procedure. EDAS involves dissecting out blood vessels on the scalp and laying them directly on the brain to encourage growth of new vessels.