Metastasis is the movement or spreading of cancer cells from one organ or tissue to another. Cancer cells usually spread through the blood or the lymph system.
If a cancer spreads, it is said to have "metastasized."
Metastatic cancer; Cancer metastases
Whether or not cancer cells spread to other parts of the body depends on many things, including:
- The type of cancer
- The stage of the cancer
- Original location of the cancer
Treatment depends on the type of cancer and where it has spread.
Doroshow JH. Approach to the patient with cancer. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 179.
Rankin EB, Erler J, Giaccia AJ. The cellular microenvironment and metastases. In: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff's Clinical Oncology. 5th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 3.
Sanford DE, Goedegebuure SP, Eberlein TJ. Tumor biology and tumor markers. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 20th ed. Philadelphia, PA: Elsevier; 2017:chap 28.