Heart disease: Research Studies

9 Related Result(s)

  1. ABSORB III Trial to test the Bioresorbable Vascular Scaffold (BVS)

    ABSORB III will evaluate the safety and effectiveness of the Absorb Bioresorbable Vascular Scaffold (BVS) System compared to the XIENCE in the treatment of...

  2. Pragmatic Phase III Randomized Trial of Proton Vs. Photon Therapy for Patients with Non-Metastatic Breast Cancer Receiving Comprehensive Nodal Radiation: A Radiotherapy Comparative Effectiveness (RADCOMP) Consortium Trial

    To assess the effectiveness of proton vs. photon therapy in reducing major cardiovascular events (MCE), defined as atherosclerotic coronary heart disease or...

  3. Women’s Ischemia Trial to Reduce Events in Non-Obstructive CAD (WARRIOR)

    The purpose of this research study is to determine if intensive medical therapy is better than usual medical care in women who have signs and symptoms of...

  4. Carvedilol in Preventing Heart Failure in Childhood Cancer Survivors

    This randomized phase IIb trial studies how well low-dose carvedilol works in preventing heart failure in cancer survivors exposed to high dose...

  5. Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

    The purpose of this study is to look at the effects of dexrazoxane hydrochloride on biomarkers associated with cardiomyopathy and heart failure after cancer...

  6. A Study of Vericiguat in Participants With Heart Failure With Reduced Ejection Fraction (VICTORIA)

    The purpose of this research study is to determine the safety and effectiveness of an experimental study drug (MK-1242) for the treatment of heart failure. ...

  7. Phase 1/2 Study of Liposomal Annamycin for the Treatment of Subjects with Acute Myeloid Leukemia (AML) that is Refractory to or Relapsed after Standard Induction Therapy

    This is a multi-center, open-label, dose escalation study that will determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of...

  8. A Phase II Study of Dose-Dense Gemcitabine Plus Cisplatin (ddGC) in Patients With Muscle-Invasive Bladder Cancer With Bladder Preservation for Those Patients Whose Tumors Harbor Deleterious DNA Damage Response (DDR) Gene Alterations

    This phase II trial studies how well gemcitabine hydrochloride and cisplatin work in treating participants with invasive bladder urothelial cancer. Drugs...

  9. Contribution of Pain Catastrophizing to Race Group Differences in Pain and Pain-Related Brain Responses in Older Adults with Knee OA

    Research participants with knee pain on most days needed. Compensation will be provided. ...