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Gastrointestinal bleeding

Definition

Gastrointestinal (GI) bleeding refers to any bleeding that starts in the gastrointestinal tract.

Bleeding may come from any site along the GI tract, but is often divided into:

  • Upper GI bleeding: The upper GI tract includes the esophagus (the tube from the mouth to the stomach), stomach, and first part of the small intestine.
  • Lower GI bleeding: The lower GI tract includes much of the small intestine, large intestine or bowels, rectum, and anus.

Alternative Names

Lower GI bleeding; GI bleeding; Upper GI bleeding; Hematochezia

Considerations

The amount of GI bleeding may be so small that it can only be detected on a lab test, such as the fecal occult blood test. Other signs of GI bleeding include:

  • Dark, tarry stools
  • Larger amounts of blood passed from the rectum
  • Small amounts of blood in the toilet bowl, on toilet paper, or in streaks on stool (feces)
  • Vomiting blood

Massive bleeding from the GI tract can be dangerous. However, even very small amounts of bleeding that occur over a long period of time can lead to problems such as anemia or low blood counts.

Once a bleeding site is found, many therapies are available to stop the bleeding or treat the cause.

Causes

GI bleeding may be due to conditions that are not serious, including:

  • Anal fissure
  • Hemorrhoids

GI bleeding may also be a sign of more serious diseases and conditions. These may include cancers of the GI tract, such as:

  • Cancer of the colon
  • Cancer of the small intestine
  • Cancer of the stomach
  • Intestinal polyps (a pre-cancerous condition)

Other causes of GI bleeding may include:

  • Abnormal blood vessels in the lining of the intestines (also called angiodysplasia)
  • Bleeding diverticulum, or diverticulosis
  • Crohn disease or ulcerative colitis
  • Esophageal varices
  • Esophagitis
  • Gastric (stomach) ulcer
  • Intussusception (bowel telescoped on itself)
  • Mallory-Weiss tear
  • Meckel diverticulum
  • Radiation injury to the bowel

Home Care

There are home stool tests for microscopic blood that may be recommended for people with anemia or for colon cancer screening.

When to Contact a Medical Professional

Contact your health care provider if:

  • You have black, tarry stools (this may be a sign of GI bleeding)
  • You have blood in your stool
  • You vomit blood or you vomit material that looks like coffee grounds

What to Expect at Your Office Visit

Your provider may discover GI bleeding during an exam at your office visit.

GI bleeding can be an emergency condition that requires immediate medical care. Treatment may involve:

  • Blood transfusions.
  • Fluids and medicines through a vein.
  • Esophagogastroduodenoscopy (EGD). A thin tube with a camera on the end is passed through your mouth into your esophagus, stomach, and small intestine.
  • A tube is placed through your mouth into the stomach to drain the stomach contents (gastric lavage).

Once your condition is stable, you will have a physical exam and a detailed exam of your abdomen. You will also be asked questions about your symptoms, including:

  • When did you first notice symptoms?
  • Did you have black, tarry stools or red blood in the stools?
  • Have you vomited blood?
  • Did you vomit material that looks like coffee grounds?
  • Do you have a history of peptic or duodenal ulcers?
  • Have you ever had symptoms like this before?
  • What other symptoms do you have?

Tests that may be done include:

  • Abdominal CT scan
  • Abdominal MRI scan
  • Abdominal x-ray
  • Angiography
  • Bleeding scan (tagged red blood cell scan)
  • Blood clotting tests
  • Capsule endoscopy (camera pill that is swallowed to look at the small intestine)
  • Colonoscopy
  • Complete blood count (CBC), clotting tests, platelet count, and other laboratory tests
  • Enteroscopy
  • Sigmoidoscopy
  • EGD or esophago-gastro endoscopy

Gallery

GI bleeding - series - Normal anatomy
The gastrointestinal tract starts at the mouth, which leads to the esophagus, stomach, small intestine, colon, and finally, the rectum and anus. The GI tract is a long, hollow, muscular tube through which food passes, nutrients are absorbed, and wastes are eliminated.
Fecal occult blood test
A fecal occult blood test is a noninvasive test that detects the presence of hidden blood in the stool. Blood in the stool that is not visible is often the first, and in many cases the only, warning sign that a person has colorectal disease, including colon cancer.

References

Kovacs TO, Jensen DM. Gastrointestinal hemorrhage. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 126.

Meguerdichian DA, Goralnick E. Gastrointestinal bleeding. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018:chap 27.

Savides TJ, Jensen DM. Gastrointestinal bleeding. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 20.

Last reviewed January 14, 2021 by Michael M. Phillips, MD, Emeritus Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team..

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