D and C: Research Studies

434 Related Result(s)

  1. A focus group study to explore the feasibility of a mHealth application to monitor and manage anxiety and mood symptoms of women during their pregnancy and postpartum period

    The purpose of this research study is to assess the feasibility and acceptance of a mobile phone-based (mHealth) application to assess anxiety and mood...

  2. A Randomized, Controlled, Open-label, Single-ascending Dose, Phase I/II Study to Investigate the Safety and Tolerability, and Efficacy of Intravenous SGT-001 in Male Adolescents and Children With Duchenne Muscular Dystrophy

    The purpose of this research study is to evaluate a new investigational product called “SGT-001” which is designed to target the underlying cause of DMD in...

  3. NCAA-DoD Grand Alliance: CARE Consortium- Cumulative and persistent intermediate effects of concussion and head impact exposure in CARE Consortium Military Service Academy members and NCAA athletes: Saliva Collection Protocol

    The purpose of this study is to address important public health questions surrounding the intermediate cumulative (alterations over a collegiate career) and...

  4. (CNV_2017_01) A Prospective, Multi-Center, Single Arm Study to obtain “real world” clinical data and characterize the acute and long-term performance of the MICRUSFRAME and GALAXY coils including the PulseRider Aneurysm Neck Reconstruction device for the endovascular treatment of intracranial aneurysms

    The objective of this study is to obtain “real world” clinical data and characterize the acute and long-term performance of the MICRUSFRAME and GALAXY coils...

  5. Phase 1 Dose Escalation and Randomized Phase 2 Trial of Carboplatin and Gemcitabine With or Without VX-970 in First Recurrence Platinum-Sensitive Epithelial Ovarian, Peritoneal, and Fallopian Tube Cancer

    This randomized phase I/II trial studies the side effects and how well carboplatin and gemcitabine hydrochloride with or without ATR kinase inhibitor VX-970...

  6. A Phase III, Randomized, Placebo-Controlled, Multi-Centre Study Evaluating the Safety, Tolerability and Efficacy of Combination Treatment of BL-8040 and G-GSF as Compared to Placebo and G-CSF for thE MobilizatioN of HematopoiEtic Stem Cells for Autologous TransplantatIon in SubjectS With Multiple Myeloma - The GENESIS Study

    A total of 207 subjects will be randomized into the study which will employ a double-blind placebo-controlled setting to assess the efficacy and safety of G...

  7. A Prospective Trial To Study Rates of Lymphedema And Regional Recurrence After Sentinel Lymph Node Biopsy and Sentinel Lymph Node Biopsy Followed By Axillary Lymph Node Dissection With and Without Axillary Reverse Mapping

    This phase III trial studies how well axillary reverse mapping works in preventing lymphedema in patients with breast cancer undergoing axillary lymph node...

  8. PNOC-013: A Safety and Pharmacokinetic Study of Single Agent REGN2810 in Pediatric Patients with Relapsed or Refractory Solid or Central Nervous System (CNS) Tumors and a Safety and Efficacy Trial of REGN2810 in Combination with Radiotherapy in Pediatric Patients with Newly Diagnosed Diffuse Intrinsic Pontine Glioma, Newly Diagnosed High-Grade Glioma, or Recurrent High-Grade Glioma

    This study is being done to test if cemiplimab-rwlc (“study drug”) can reduce the size of your tumor by helping the immune system destroy the tumor. The...

  9. (HeadStart 4) Newly Diagnosed Children (Less than 10 Years Old) With Medulloblastoma and Other Central Nervous System Primitive Neuro-Ectodermal Tumors: Clinical and Molecular Risk-Tailored Intensive and Compressed Induction Chemotherapy Followed by Consolidation with Either Single-Cycle (Low Risk Patients) or Randomization (High Risk Patients) to either Single-Cycle or to Three Tandem Cycles of Marrow-Ablative Chemotherapy with Autologous Hematopoietic Progenitor Cell Rescue

    This research study will compare two different treatment regimens to see which is better for treating children with different types of brain tumors called...

  10. A Phase III, Randomized, Open-label Study to Evaluate Pembrolizumab as Neoadjuvant Therapy and in Combination With Standard of Care as Adjuvant Therapy for Stage III-IVA Resectable Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

    This is a randomized, active-controlled, open-label study of pembrolizumab (Pembro) given prior to surgery and pembrolizumab in combination with standard of...

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