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Chemical pneumonitis

Definition

Chemical pneumonitis is inflammation of the lungs or breathing difficulty due to inhaling chemical fumes or breathing in and choking on certain chemicals.

Alternative Names

Aspiration pneumonia - chemical

Causes

Many chemicals used in the home and workplace can cause pneumonitis.

Some common dangerous inhaled substances include:

  • Chlorine gas (breathed in from cleaning materials such as chlorine bleach, during industrial accidents, or near swimming pools)
  • Grain and fertilizer dust
  • Noxious fumes from pesticides
  • Smoke (from house fires and wildfires)

There are two types of pneumonitis:

  • Acute pneumonitis occurs suddenly after breathing in the substance.
  • Long-term (chronic) pneumonitis occurs after exposure to low levels of the substance over a long time. This causes inflammation and may lead to stiffness of the lungs. As a result, the lungs start to lose their ability to get oxygen to the body. Untreated, this condition can cause respiratory failure and death.

Chronic aspiration of acid from the stomach and exposure to chemical warfare can also lead to chemical pneumonitis.

Symptoms

Acute symptoms may include:

  • Air hunger (feeling that you cannot get enough air)
  • Breathing that sounds wet or gurgling (abnormal lung sounds)
  • Cough
  • Difficulty breathing
  • Unusual sensation (possibly burning feeling) in the chest

Chronic symptoms may include:

Exams and Tests

The following tests help determine how severely the lungs are affected:

Treatment

Treatment is focused on reversing the cause of inflammation and reducing symptoms. Corticosteroids may be given to reduce inflammation, often before long-term scarring occurs.

Antibiotics are usually not helpful or needed, unless there is a secondary infection. Oxygen therapy may be helpful.

In cases of swallowing and stomach problems, eating small meals in the upright position can help. In severe cases, a feeding tube in the stomach is needed, although this does not always completely prevent aspiration into the lungs.

Outlook (Prognosis)

The outcome depends on the chemical, the severity of exposure, and whether the problem is acute or chronic.

Possible Complications

Respiratory failure and death can occur.

When to Contact a Medical Professional

Contact your health care provider if you have trouble breathing after inhaling (or possibly inhaling) any substance.

Prevention

Only use household chemicals as directed, and always in well-ventilated areas with proper protective equipment. Never mix ammonia and bleach.

Follow workplace rules for breathing masks and wear the right mask. People who work near fire should take care to limit their exposure to smoke or gases.

Be careful about giving mineral oil to anyone who might choke on it (children or older people).

Sit up while eating and don't lie down right after eating if you have swallowing problems.

Do not siphon gas, kerosene, or other toxic liquid chemicals.

Gallery

Lungs
The major features of the lungs include the bronchi, the bronchioles and the alveoli. The alveoli are the microscopic blood vessel-lined sacks in which oxygen and carbon dioxide gas are exchanged.
Coronavirus
Coronaviruses are a family of viruses. Infection with these viruses can cause mild to moderate respiratory illnesses such as the common cold. Some coronaviruses may cause severe illness and lead to pneumonia or even death.

References

Christiani DC. Physical and chemical injuries of the lungs. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 88.

Gibbs AR, Attanoos RL. Environmental- and toxin-induced lung diseases. In: Zander DS, Farver CF, eds. Pulmonary Pathology. 2nd ed. Philadelphia, PA: Elsevier; 2018:chap 18.

Kushchner WG, Blanc PD. Acute responses to toxic exposures. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 103.

Tarlo SM. Occupational lung disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 87.

Last reviewed July 31, 2022 by Denis Hadjiliadis, MD, MHS, Paul F. Harron, Jr. Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team..

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