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Aortic arch syndrome
The aortic arch is the top part of the main artery carrying blood away from the heart. Aortic arch syndrome refers to a group of signs and symptoms associated with structural problems in the arteries that branch off the aortic arch.
Subclavian artery occlusive syndrome; Carotid artery occlusion syndrome; Subclavian steal syndrome; Vertebral-basilar artery occlusive syndrome; Takayasu disease; Pulseless disease
Aortic arch syndrome problems can be due to trauma, blood clots, or malformations that develop before birth. These defects result in abnormal blood flow to the head, neck, or arms.
In children, there are many types of aortic arch syndromes, including:
- Congenital absence of a branch of the aorta
- Isolation of the subclavian arteries
- Vascular rings
An inflammatory disease called Takayasu syndrome may result in narrowing (stenosis) of the vessels of the aortic arch. This typically occurs in women and girls. This disease is seen more often in people of Asian descent.
Symptoms vary according to which artery or other structure that has been affected. Symptoms may include:
- Blood pressure changes
- Breathing problems
- Dizziness, blurred vision, weakness, and other brain and nervous system (neurological) changes
- Numbness of an arm
- Reduced pulse
- Swallowing problems
- Transient ischemic attacks (TIA)
Surgery is most often needed to treat the underlying cause of aortic arch syndrome.
Braverman AC, Schermerhorn M. Diseases of the aorta. In: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Philadelphia, PA: Elsevier Saunders; 2018:chap 63.
Lederle FA. Diseases of the aorta. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 78.