Anna De Benedetto, MD

Anna De Benedetto, MD

(352) 594-1500

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Publications

Whole genome sequencing identifies novel genetic mutations in patients with eczema herpeticum.
Allergy
2021

Tight junctions in the skin: still a lot to learn.
The British journal of dermatology
2021

Targetoid clinical morphology as a diagnostic clue of the lichenoid histopathologic subtype of pigmented purpuric dermatosis.
JAAD case reports
2021

Isotretinoin-induced inflammation of the urethral meatus.
Dermatologic therapy
2021

Eruptive agminated nevi in a successfully treated Langerhans cell histiocytosis patient.
Pediatric dermatology
2021

Allergic Contact Dermatitis Due to Thiourea Derivatives in a Gun Holster.
Dermatitis : contact, atopic, occupational, drug
2021

Topical doxycycline monohydrate hydrogel 1% targeting proteases/PAR2 pathway is a novel therapeutic for atopic dermatitis.
Experimental dermatology
2020

The role of bacterial skin infections in atopic dermatitis: expert statement and review from the International Eczema Council Skin Infection Group.
The British journal of dermatology
2020

Sunless tanner caused persistent hyperpigmented patches on the hands.
Cutis
2020

Peptides Derived from the Tight Junction Protein CLDN1 Disrupt the Skin Barrier and Promote Responsiveness to an Epicutaneous Vaccine.
The Journal of investigative dermatology
2020

Atopic dermatitis in the elderly: a review of clinical and pathophysiological hallmarks.
The British journal of dermatology
2020

Update on protease-activated receptor 2 in cutaneous barrier, differentiation, tumorigenesis and pigmentation, and its role in related dermatologic diseases.
Experimental dermatology
2019

The use of selective Th2 blocker dupilumab for the treatment of atopic dermatitis in a heart transplant patient: Case report.
Dermatologic therapy
2019

Collagenous and elastotic marginal plaques of the hand: A potential clue to the diagnosis of alkaptonuria.
Journal of cutaneous pathology
2019

Antagonistic Effects of IL-4 on IL-17A-Mediated Enhancement of Epidermal Tight Junction Function.
International journal of molecular sciences
2019

Allergen Immunotherapy and Atopic Dermatitis: the Good, the Bad, and the Unknown.
Current allergy and asthma reports
2019

Patients with Atopic Dermatitis Colonized with Staphylococcus aureus Have a Distinct Phenotype and Endotype.
The Journal of investigative dermatology
2018

Activation of protease-activated receptor 2 leads to impairment of keratinocyte tight junction integrity.
The Journal of allergy and clinical immunology
2018

Doxycycline as an anti-inflammatory agent: updates in dermatology.
Journal of the European Academy of Dermatology and Venereology : JEADV
2017

Atopic Dermatitis in Animals and People: An Update and Comparative Review.
Veterinary sciences
2017

ΔNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis.
Cell death and differentiation
2016

Histamine and Skin Barrier: Are Histamine Antagonists Useful for the Prevention or Treatment of Atopic Dermatitis?
Journal of clinical medicine
2015

Epidermal tight junctions in health and disease.
Tissue barriers
2015

The cutaneous innate immune response in patients with atopic dermatitis.
The Journal of allergy and clinical immunology
2013

Quantification of quantum dot murine skin penetration with UVR barrier impairment.
Nanotoxicology
2013

Activation of epidermal toll-like receptor 2 enhances tight junction function: implications for atopic dermatitis and skin barrier repair.
The Journal of investigative dermatology
2013

Skin barrier disruption: a requirement for allergen sensitization?
The Journal of investigative dermatology
2012

Aldo-keto reductase 1C3 is expressed in differentiated human epidermis, affects keratinocyte differentiation, and is upregulated in atopic dermatitis.
The Journal of investigative dermatology
2012

Tight junction defects in patients with atopic dermatitis.
The Journal of allergy and clinical immunology
2011

Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis.
The Journal of allergy and clinical immunology
2011

Polyinosinic:polycytidylic acid induces protein kinase D-dependent disassembly of apical junctions and barrier dysfunction in airway epithelial cells.
The Journal of allergy and clinical immunology
2011

Mannan-binding lectin levels and activity are not altered in atopic dermatitis patients with a history of eczema herpeticum.
Dermatology research and practice
2011

Atopic dermatitis: a disease caused by innate immune defects?
The Journal of investigative dermatology
2009

Filaggrin expression in oral, nasal, and esophageal mucosa.
The Journal of investigative dermatology
2008

Bullous Wells syndrome.
Journal of the European Academy of Dermatology and Venereology : JEADV
2006

Coexisting pemphigus vulgaris and pemphigus foliaceus in the same patient.
International journal of dermatology
2005

Keratinocytes in atopic dermatitis: inflammatory signals.
Current allergy and asthma reports
2004

Lupus vulgaris developing at the site of misdiagnosed scrofuloderma.
Journal of the European Academy of Dermatology and Venereology : JEADV
2003

Alcoholism as a trigger of multiple symmetric lipomatosis?
Journal of the European Academy of Dermatology and Venereology : JEADV
2003

A minimal form of Proteus syndrome presenting with macrodactyly and hand hyperplasia.
European journal of dermatology : EJD
2003

Research Interests

Director of Dermatology Clinical Trial Unit.

Basic science: investigating regulation of skin barrier function/composition and role in atopic dermatitis