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Amniotic fluid

Definition

Amniotic fluid is a clear, slightly yellowish liquid that surrounds the unborn baby (fetus) during pregnancy. It is contained in the amniotic sac.

Information

While in the womb, the baby floats in the amniotic fluid. The amount of amniotic fluid is greatest at about 34 weeks into the pregnancy (34 weeks gestation), when it averages 800 mL. About 600 mL of amniotic fluid surrounds the baby at full term (40 weeks gestation).

The amniotic fluid constantly moves (circulates) as the baby swallows and "inhales" the fluid, and then releases it.

The amniotic fluid helps:

  • The developing baby to move in the womb, which allows for proper bone growth
  • The lungs to develop properly
  • Prevent pressure on the umbilical cord
  • Keep a constant temperature around the baby, protecting from heat loss
  • Protect the baby from outside injury by cushioning sudden blows or movements

Too much amniotic fluid is called polyhydramnios. This condition can occur with multiple pregnancies (twins or triplets), congenital anomalies (problems that exist when the baby is born), or gestational diabetes.

Too little amniotic fluid is known as oligohydramnios. This condition may occur with late pregnancies, ruptured membranes, placental dysfunction, or fetal abnormalities.

Abnormal amounts of amniotic fluid may cause the health care provider to watch the pregnancy more carefully. Removing a sample of the fluid through amniocentesis can provide information about the sex, health, and development of the fetus.

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Amniocentesis
Amniocentesis is used to determine the health of an unborn baby. Amniotic fluid contains cells that are normally shed from the fetus. Samples of these cells are obtained by withdrawing some amniotic fluid. The chromosome analysis of these cells can be performed to determine abnormalities. In addition, the cells may be cultured and analyzed for enzymes, or for other materials that may indicate genetically transmitted diseases. Other studies can be done directly on the amniotic fluid including measurement of alpha-fetoprotein.
Amniocentesis
Amniocentesis is used to determine the health of an unborn baby. Amniotic fluid contains cells that are normally shed from the fetus. Samples of these cells are obtained by withdrawing some amniotic fluid. The chromosome analysis of these cells can be performed to determine abnormalities. In addition, the cells may be cultured and analyzed for enzymes, or for other materials that may indicate genetically transmitted diseases. Other studies can be done directly on the amniotic fluid including measurement of alpha-fetoprotein.
Polyhydramnios
Polyhydramnios may occur when a fetus cannot swallow a normal amount of amniotic fluid due to a gastrointestinal, neurological, or other problem.
Amniocentesis
Amniocentesis is used to determine the health of an unborn baby. Amniotic fluid contains cells that are normally shed from the fetus. Samples of these cells are obtained by withdrawing some amniotic fluid. The chromosome analysis of these cells can be performed to determine abnormalities. In addition, the cells may be cultured and analyzed for enzymes, or for other materials that may indicate genetically transmitted diseases. Other studies can be done directly on the amniotic fluid including measurement of alpha-fetoprotein.

References

Burton GJ, Sibley CP, Jauniaux ERM. Placental anatomy and physiology. In: Landon MB, Galan HL, Jauniaux ERM, et al, eds. Gabbe's Obstetrics: Normal and Problem Pregnancies. 8th ed. Philadelphia, PA: Elsevier; 2021:chap 1.

Gilbert WM. Amniotic fluid disorders. In: Landon MB, Galan HL, Jauniaux ERM, et al, eds. Gabbe's Obstetrics: Normal and Problem Pregnancies. 8th ed. Philadelphia, PA: Elsevier; 2021:chap 28.

Ross MG, Beall MH. Amniotic fluid dynamics. In: Lockwood CJ, Copel JA, Dugoff L, et al, eds. Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice. 9th ed. Philadelphia, PA: Elsevier; 2023:chap 4.

Last reviewed November 10, 2022 by John D. Jacobson, MD, Department of Obstetrics and Gynecology, Loma Linda University School of Medicine, Loma Linda, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team..

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