The purpose of this study is to evaluate the anti-tumor effects of TAR-200 in combination with intravenous (IV) cetrelimab and IV cetrelimab alone.
- Investigator
- Paul L Crispen
- Status
- Accepting Candidates
- Ages
- 18 Years - N/A
- Sexes
- All
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Aloe is an extract from the aloe plant. It is used in many skin care products. Aloe poisoning occurs when someone swallows this substance. However, aloe is not very poisonous.
This article is for information only. DO NOT use it to treat or manage an actual poison exposure. If you or someone you are with has an exposure, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Skin and sunburn treatments
The substances that can be harmful are:
Aloe is found in many different products, including:
Other products may also contain aloe.
Symptoms of aloe poisoning include:
Stop using the product.
Seek medical help right way. DO NOT make the person throw up unless poison control or a health care provider tells you to.
Have this information ready:
Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.
This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.
Take the container with you to the hospital, if possible.
The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated.
The person may receive:
How well someone does depends on how much aloe they swallowed and how quickly they receive treatment. The faster medical help is given, the better the chance for recovery.
Aloe is not very poisonous. Treatment is usually not needed. However, if you swallow it, you will likely have diarrhea.
A small number of people have an allergic reaction to aloe, which can be dangerous. Get medical help if a rash, throat tightness, difficulty breathing, or chest pain develop.
Chan M. Popular herbs and nutritional supplements. In: Kellerman RD, Rakel DP, eds. Conn's Current Therapy 2022. Philadelphia, PA: Elsevier 2022:1460-1468.
Davison K, Frank BL. Ethnobotany: plant-derived medical therapy. In: Auerbach PS, Cushing TA, Harris NS, eds. Auerbach's Wilderness Medicine. 7th ed. Philadelphia, PA: Elsevier; 2017:chap 68.
Hanaway PJ. Irritable bowel syndrome. In: Rakel D, ed. Integrative Medicine. 4th ed. Philadelphia, PA: Elsevier; 2018:chap 41.
Murray MT. Aloe vera (Cape Aloe). In: Pizzorno JE, Murray MT, eds. Textbook of Natural Medicine. 5th ed. St Louis, MO: Elsevier; 2021:chap 52.
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The purpose of this study is to evaluate the anti-tumor effects of TAR-200 in combination with intravenous (IV) cetrelimab and IV cetrelimab alone.
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